Date published: 2026-4-5

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GDF-8 Antibodies

Santa Cruz Biotechnology delivers a wide array of GDF-8 monoclonal antibodies for research focused on understanding muscle growth and development. GDF-8 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GDF-8, also known as myostatin, is a member of the transforming growth factor-beta (TGF-β) superfamily and plays a crucial role in regulating muscle growth and development. As a negative regulator of muscle mass, GDF-8 has significant implications in various muscle-wasting conditions and diseases. Research involving GDF-8 continues to reveal important insights about muscle biology and potential therapeutic approaches. Understanding GDF-8 function is essential for developing strategies aimed at muscle regeneration and treating muscle-related disorders. Investigating GDF-8 signaling pathways helps illuminate the molecular mechanisms controlling muscle development and homeostasis. Current research explores how GDF-8 regulation impacts muscle stem cell function and tissue repair. Santa Cruz Biotechnology monoclonal antibodies for GDF-8 enable researchers to advance scientific understanding of muscle biology and its implications for human health.

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GDF-8 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GDF-8 Antibody (1L4)

sc-134345mouse IgG2a κ243-310 (h)WB, IP, ELISAm, r, h
11
(4)

GDF-8/11 Antibody (H-9)

sc-393335mouse IgG2a κ347-376 (m)WB, IP, IF, IHC(P), ELISAm, r, h
12
(1)

GDF-8/11 Antibody (A-1)

sc-398333mouse IgG2b κ258-270 (h)WB, IP, IF, ELISAm, r, h
4
(1)

GDF-8 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GDF-8 CRISPR/Cas9 KO Plasmid (h)

sc-400693hGene KnockoutGFP0
(0)

GDF-8 HDR Plasmid (h)

sc-400693-HDRhHomology Directed RepairPuromycin0
(0)

GDF-8 Double Nickase Plasmid (h)

sc-400693-NIChGene KnockoutPuromycin0
(0)

GDF-8 Double Nickase Plasmid (h2)

sc-400693-NIC-2hGene KnockoutPuromycin0
(0)

GDF8 CRISPR/Cas9 KO Plasmid (m)

sc-421724mGene KnockoutGFP
1
(0)

GDF8 HDR Plasmid (m)

sc-421724-HDRmHomology Directed RepairPuromycin
1
(0)

GDF-8 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GDF-8 CRISPR Activation Plasmid (h)

sc-400693-ACThGene ActivationPuro, Blast, Hygro0
(0)

GDF-8 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GDF-8 siRNA (h)

sc-39774hGene SilencingN/A0
(0)

GDF-8 shRNA Plasmid (h)

sc-39774-SHhGene SilencingPuromycin0
(0)

GDF-8 shRNA (h) Lentiviral Particles

sc-39774-VhGene SilencingPuromycin0
(0)

GDF-8 siRNA (m)

sc-39775mGene SilencingN/A
5
(0)

GDF-8 shRNA Plasmid (m)

sc-39775-SHmGene SilencingPuromycin
5
(0)

GDF-8 shRNA (m) Lentiviral Particles

sc-39775-VmGene SilencingPuromycin
5
(0)