GDE3 Activators
GDE3 activators are a diverse group of chemicals that can activate the GDE3 protein. These chemicals can activate GDE3 by binding to its receptor, by activating signaling pathways that lead to the activation of GDE3, or by both of these mechanisms.
Retinoic acid (RA) is a metabolite of vitamin A that plays a role in cell differentiation and development. RA can activate GDE3 by binding to its receptor, RAR. Activation of RAR leads to the activation of the PI3K/Akt signaling pathway, which in turn activates GDE3. RA has been shown to induce differentiation and apoptosis in a variety of cell types, including epithelial cells, fibroblasts, and cancer cells. RA is also involved in the regulation of cell growth and proliferation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine 1-phosphate (S1P) is a bioactive lipid that plays a role in cell migration, proliferation, and survival. S1P can activate GDE3 by binding to its receptor, S1PR1. Activation of S1PR1 leads to the activation of the MAPK signaling pathway, which in turn activates GDE3. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid (RA) is a metabolite of vitamin A that plays a role in cell differentiation and development. RA can activate GDE3 by binding to its receptor, RAR. Activation of RAR leads to the activation of the PI3K/Akt signaling pathway, which in turn activates GDE3. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria. LPS can activate GDE3 by binding to its receptor, TLR4. Activation of TLR4 leads to the activation of the MAPK and NF-kappaB signaling pathways, which in turn activate GDE3. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin is a hormone that plays a role in glucose metabolism. Insulin can activate GDE3 by binding to its receptor, INSR. Activation of INSR leads to the activation of the PI3K/Akt signaling pathway, which in turn activates GDE3. | ||||||