Guanylate-binding protein 7 (GBP7) is a protein that in humans is encoded by the GBP7 gene. As a member of the guanylate-binding protein (GBP) family, it is part of the larger superfamily of large GTPases, proteins that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP). GTPases are involved in a variety of cellular processes, including cell division, signal transduction, and protein synthesis.GBP7 shares a common structural feature with other GBPs, which is the presence of two tandem GTPase domains. This is unusual as most GTPases typically feature a single such domain.
GBPs are often induced by interferons, proteins that are central to the body's defense against viral infections. They are known to interfere with the replication of several pathogens, including bacteria and viruses, within host cells.While the specific functions and interactions of GBP7 are still under investigation, its membership in the GBP family suggests that it may play a role in the immune response to infection. Further research is needed to elucidate the precise roles of GBP7 in cellular processes and disease states.In summary, GBP7 is a member of the guanylate-binding protein family and likely plays a role in cellular processes related to immunity and possibly other functions. Its exact roles and potential involvement in disease are areas of ongoing research.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
Poly I:C is a synthetic analog of double-stranded RNA and can mimic viral infection, leading to the induction of interferon-stimulated genes. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS is a component of the outer membrane of Gram-negative bacteria and can stimulate the immune system, potentially increasing GBP7 expression. | ||||||
Imiquimod | 99011-02-6 | sc-200385 sc-200385A | 100 mg 500 mg | $67.00 $284.00 | 6 | |
Imiquimod is an immune response modifier that can induce interferon production, which may lead to the upregulation of GBP7. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
Resiquimod is a toll-like receptor agonist that can enhance the production of interferons, possibly influencing GBP7 expression. | ||||||
Gardiquimod | 1020412-43-4 | sc-221663 sc-221663A sc-221663B sc-221663C sc-221663D sc-221663E sc-221663F | 25 mg 50 mg 100 mg 250 mg 5 g 10 g 25 g | $157.00 $282.00 $516.00 $1177.00 $20138.00 $32779.00 $70753.00 | 1 | |
Gardiquimod is a TLR7 agonist that can trigger antiviral responses, including the upregulation of interferon-stimulated genes like GBP7. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid has been shown to affect immune responses and gene expression, potentially influencing GBP7 levels. | ||||||