Galectin-2 inhibitors belong to a class of chemical compounds designed to specifically target and modulate the activity of galectin-2, a protein belonging to the galectin family. Galectins are a group of carbohydrate-binding proteins that play crucial roles in various physiological and pathological processes, including cell adhesion, immune response, and inflammation. Galectin-2, in particular, has been implicated in mediating interactions between cells and the extracellular matrix, thereby influencing cell migration, tissue homeostasis, and immune cell function.
Galectin-2 functions by disrupting the binding of galectin-2 to its carbohydrate ligands. These ligands are often present on the cell surface and extracellular matrix, and the interaction with galectin-2 can modulate cell signaling and adhesion. By selectively inhibiting galectin-2, these compounds aim to interfere with the molecular events mediated by galectin-2, potentially influencing cellular processes in which galectin-2 is involved. The development of galectin-2 inhibitors represents a targeted approach to manipulate specific cellular functions associated with galectin-2, contributing to the broader understanding of galectin biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $50.00 $110.00 $145.00 $248.00 $598.00 | 1 | |
Interacts with calcium ions which can be critical for the carbohydrate-recognition domains of galectins to maintain their structure. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
May modulate protein glycosylation, thereby altering the interaction potential of galectins with glycoproteins. | ||||||
Phenylbutazone | 50-33-9 | sc-204843 | 5 g | $32.00 | 1 | |
May alter glycosylation patterns in cells, influencing galectin interactions. | ||||||
Castanospermine | 79831-76-8 | sc-201358 sc-201358A | 100 mg 500 mg | $184.00 $632.00 | 10 | |
An indolizidine alkaloid that inhibits glycosidase enzymes, potentially modifying galectin binding partners. | ||||||
Swainsonine | 72741-87-8 | sc-201362 sc-201362C sc-201362A sc-201362D sc-201362B | 1 mg 2 mg 5 mg 10 mg 25 mg | $138.00 $251.00 $631.00 $815.00 $1832.00 | 6 | |
An indolizidine alkaloid that inhibits mannosidase enzymes, affecting glycosylation and potentially galectin function. | ||||||
Deoxynojirimycin | 19130-96-2 | sc-201369 sc-201369A | 1 mg 5 mg | $73.00 $145.00 | ||
An iminosugar that inhibits glycosidase enzymes, which may affect galectin-glycoprotein interactions. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
A flavonoid that influences glycosylation and could modulate galectin interactions with glycoproteins. | ||||||
Catechin | 154-23-4 | sc-205624 sc-205624A | 1 mg 5 mg | $133.00 $299.00 | 3 | |
A flavonoid that could alter protein glycosylation, potentially affecting galectin function. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Known to affect glycosylation pathways in cells, which could influence galectin interactions. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A curcuminoid compound that may affect protein glycosylation, indirectly affecting galectin function. | ||||||