GAD-25 Activators
GAD-25 Activators encompass a range of chemical compounds that facilitate the enhancement of GAD-25's catalytic conversion of glutamate into gamma-Aminobutyric acid (GABA). Pyridoxal phosphate, a vital cofactor of GAD-25, directly augments its functional activity, ensuring the enzyme's optimal catalytic performance. Glutamate, the very substrate GAD-25 acts upon, inherently increases the enzyme's activity by providing the necessary component for GABA synthesis, while L-Theanine and Taurine potentially raise the substrate availability, further bolstering GAD-25's role in GABA production.
Vitamin B6 is essential for the synthesis of pyridoxal phosphate, thus indirectly enhancing GAD-25 functionality by ensuring a consistent supply of the active cofactor. Magnesium and Zinc ions both contribute by modulating GABAergic neurotransmission in manners that can result in the allosteric enhancement of GAD-25, suggesting a more subtle yet significant influence on the enzyme's activity. Additionally, certain nutrients and extracts such as Niacinamide and Ginkgo biloba extract indirectly contribute to the upregulation of GAD-25's activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pyridoxal-5-phosphate | 54-47-7 | sc-205825 | 5 g | $102.00 | ||
Pyridoxal phosphate is a cofactor of GAD-25 and is necessary for its enzymatic activity to convert glutamate to GABA, thereby enhancing GAD-25's function in GABA synthesis. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
Glutamate serves as the substrate for GAD-25, and its availability directly increases the functional activity of GAD-25 in the synthesis of GABA. | ||||||
L-Theanine | 3081-61-6 | sc-204787 sc-204787A | 1 g 5 g | $57.00 $139.00 | 1 | |
L-Theanine is known to increase the levels of GABA in the brain. It may enhance GAD-25 activity by providing an increased substrate availability for GABA synthesis. | ||||||
Taurine | 107-35-7 | sc-202354 sc-202354A | 25 g 500 g | $47.00 $100.00 | 1 | |
Taurine can enhance GAD-25 activity by modulating the GABAergic system and potentially increasing the availability of the substrate for GABA synthesis. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is a modulator of GABAergic neurotransmission and may play a role in enhancing GAD-25 activity by allosteric modulation of the enzyme. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Niacinamide, a form of Vitamin B3, could enhance GAD-25 activity by participating in the synthesis of NAD+, which is involved in various enzymatic reactions that could indirectly support the conditions for GABA synthesis. | ||||||
Phosphatidyl-L-serine | 51446-62-9 | sc-507548 | 10 g | $45.00 | ||
Phosphatidylserine affects neurotransmitter release and could indirectly enhance GAD-25 activity by improving neuronal health and synaptic function. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
DHA, an omega-3 fatty acid, is thought to support brain health and may indirectly enhance GAD-25 activity by maintaining neuronal membrane fluidity and influencing neurotransmission. | ||||||