Date published: 2025-10-19

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FXR Antibodies

Santa Cruz Biotechnology features a diverse variety of FXR Antibodies for research focused on understanding the farnesoid X receptor (FXR) in various biological processes. Monoclonal FXR Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The farnesoid X receptor is a nuclear receptor that plays a crucial role in bile acid homeostasis, lipid metabolism, and glucose regulation. FXR is actively involved in modulating inflammatory responses and has been linked to metabolic diseases, making it a significant target for therapeutic interventions. Understanding FXR function is essential for advancing research in liver diseases, obesity, and diabetes. Researchers worldwide rely on FXR detection methods to explore cellular pathways and molecular mechanisms. Current studies of FXR continue to reveal new insights into metabolic regulation and potential therapeutic approaches. Ongoing research with FXR has highlighted its importance in maintaining cellular homeostasis and tissue function. Santa Cruz Biotechnology monoclonal FXR Antibodies enable researchers to advance scientific understanding of metabolic diseases and potential treatments.

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FXR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

FXR/NR1H4 Antibody (D-3)

sc-25309mouse IgG2a κ1-130 (h)WB, IP, IF, ELISAm, r, h
74
(20)

FXR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FXRβ CRISPR/Cas9 KO Plasmid (m)

sc-436291mGene KnockoutGFP0
(0)

FXRβ HDR Plasmid (m)

sc-436291-HDRmHomology Directed RepairPuromycin0
(0)

FXRβ Double Nickase Plasmid (m)

sc-436291-NICmGene KnockoutPuromycin0
(0)

FXRβ Double Nickase Plasmid (m2)

sc-436291-NIC-2mGene KnockoutPuromycin0
(0)

FXR/NR1H4 CRISPR/Cas9 KO Plasmid (h)

sc-417410hGene KnockoutGFP0
(0)

FXR/NR1H4 HDR Plasmid (h)

sc-417410-HDRhHomology Directed RepairPuromycin0
(0)

FXR/NR1H4 Double Nickase Plasmid (h)

sc-417410-NIChGene KnockoutPuromycin0
(0)

FXR/NR1H4 Double Nickase Plasmid (h2)

sc-417410-NIC-2hGene KnockoutPuromycin0
(0)

FXR/NR1H4 CRISPR/Cas9 KO Plasmid (m)

sc-422772mGene KnockoutGFP0
(0)

FXR/NR1H4 HDR Plasmid (m)

sc-422772-HDRmHomology Directed RepairPuromycin0
(0)

FXR/NR1H4 Double Nickase Plasmid (m)

sc-422772-NICmGene KnockoutPuromycin0
(0)

FXR/NR1H4 Double Nickase Plasmid (m2)

sc-422772-NIC-2mGene KnockoutPuromycin0
(0)

FXR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FXRβ CRISPR Activation Plasmid (m)

sc-436291-ACTmGene ActivationPuro, Blast, Hygro0
(0)

FXRβ CRISPR Activation Plasmid (m2)

sc-436291-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

FXRβ Lentiviral Activation Particles (m)

sc-436291-LACmGene ActivationPuro, Blast, Hygro0
(0)

FXRβ Lentiviral Activation Particles (m2)

sc-436291-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 CRISPR Activation Plasmid (h)

sc-417410-ACThGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 CRISPR Activation Plasmid (h2)

sc-417410-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 Lentiviral Activation Particles (h)

sc-417410-LAChGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 Lentiviral Activation Particles (h2)

sc-417410-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 CRISPR Activation Plasmid (m)

sc-422772-ACTmGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 CRISPR Activation Plasmid (m2)

sc-422772-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 Lentiviral Activation Particles (m)

sc-422772-LACmGene ActivationPuro, Blast, Hygro0
(0)

FXR/NR1H4 Lentiviral Activation Particles (m2)

sc-422772-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

FXR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

FXRβ siRNA (m)

sc-155895mGene SilencingN/A0
(0)

FXRβ shRNA Plasmid (m)

sc-155895-SHmGene SilencingPuromycin0
(0)

FXRβ shRNA (m) Lentiviral Particles

sc-155895-VmGene SilencingPuromycin0
(0)

FXR/NR1H4 siRNA (h)

sc-38848hGene SilencingN/A
17
(0)

FXR/NR1H4 shRNA Plasmid (h)

sc-38848-SHhGene SilencingPuromycin
17
(0)

FXR/NR1H4 shRNA (h) Lentiviral Particles

sc-38848-VhGene SilencingPuromycin
17
(0)

FXR/NR1H4 siRNA (m)

sc-155894mGene SilencingN/A
3
(0)

FXR/NR1H4 shRNA Plasmid (m)

sc-155894-SHmGene SilencingPuromycin
3
(0)

FXR/NR1H4 shRNA (m) Lentiviral Particles

sc-155894-VmGene SilencingPuromycin
3
(0)

FXR/NR1H4 siRNA (r)

sc-108079rGene SilencingN/A
1
(0)

FXR/NR1H4 shRNA Plasmid (r)

sc-108079-SHrGene SilencingPuromycin
1
(0)

FXR/NR1H4 shRNA (r) Lentiviral Particles

sc-108079-VrGene SilencingPuromycin
1
(0)