FNDC4 Activators refer to a specific class of chemical compounds designed or identified for their potential to modulate the activity of Fibronectin Type III Domain Containing 4 (FNDC4), also known as Irisin. FNDC4 is a protein primarily expressed in skeletal muscle and adipose tissue, and it is a precursor to irisin, a hormone-like molecule involved in various physiological processes. Irisin has been implicated in regulating energy metabolism, exercise-induced thermogenesis, and potentially influencing various aspects of metabolic health. Activating FNDC4 with these compounds entails influencing its functional interactions and biochemical activities within the cell. Typically, FNDC4 activators possess specific structural features and chemical properties that allow them to interact with FNDC4, potentially affecting its molecular functions.
Chemically, FNDC4 activators may exhibit structural diversity, reflecting the complexity of their interactions with the protein. These interactions may involve binding to specific domains or regions on FNDC4, altering its conformation, or enhancing its secretion of irisin or its interactions with downstream signaling pathways. The study of FNDC4 activators is crucial for researchers aiming to understand the molecular mechanisms underlying the regulation of energy metabolism, thermogenesis, and metabolic health. By investigating how these activators impact FNDC4, researchers can gain insights into the broader biological significance of FNDC4 and irisin in the context of cell biology and molecular physiology, particularly their roles in metabolic processes and their potential implications for overall health.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hydrocortisone | 50-23-7 | sc-300810 | 5 g | $102.00 | 6 | |
Regulates gene expression by interacting with glucocorticoid receptors, often involved in immune response modulation. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
Acts through the JAK/STAT pathway, crucial in cellular responses to cytokines and growth factors. | ||||||
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
A synthetic analog of double-stranded RNA, inducing interferons, crucial in pathogen response. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in immune process regulation through retinoic acid receptors. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Plays a role in the regulation of immune responses, a form of Vitamin D. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Involved in the inflammatory response as a prostaglandin analogue. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Alters chromatin structure and affects gene expression, including genes related to immunity. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Changes DNA methylation patterns, potentially influencing gene expression in immune pathways. | ||||||
BEZ235 | 915019-65-7 | sc-364429 | 50 mg | $211.00 | 8 | |
Involved in cell growth, metabolism, and immunity as a PI3K/Akt/mTOR pathway inhibitor. | ||||||