FLJ31818 Activators
FLJ31818 activators are a class of chemical compounds that target the protein encoded by the gene FLJ31818. This gene is part of a larger family that is characterized by various biological functions within cellular processes. FLJ31818 activators interact with the protein at a molecular level, affecting its activity within the cell. The precise mechanisms of action for these activators are often complex and involve a series of biochemical interactions that lead to the modulation of the protein's function. Typically, these activators are designed to bind selectively to the FLJ31818 protein, which can result in the alteration of its conformation, and hence, its activity within the cell. The specificity of these activators is critical as it ensures targeted modulation of the protein function without interfering with other cellular proteins which could lead to unintended consequences.
The development and study of FLJ31818 activators involve an interdisciplinary approach that includes chemistry, biochemistry, and molecular biology among others. Researchers focus on understanding the structure of the FLJ31818 protein, identifying potential binding sites for activators, and synthesizing molecules that can interact with the protein in a predictable and efficient manner. The design of these molecules is often aided by computational models that predict how the activator will interact with the protein's structure. Advanced techniques such as X-ray crystallography or NMR spectroscopy may be utilized to elucidate the binding modes of these activators. Once identified and synthesized, these activators are typically subjected to a series of assays to confirm their activity and specificity towards the FLJ31818 protein. These studies help in gaining deeper insights into the protein's role within the cell and how its activity can be modulated by small molecules.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin directly stimulates adenylyl cyclase, leading to an increase in cyclic AMP (cAMP) levels. Elevated cAMP activates protein kinase A (PKA), which can then phosphorylate various substrates, including proteins similar to FLJ31818, hence enhancing their activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which is known to phosphorylate a wide range of cellular proteins. This activation can lead to phosphorylation of proteins in the same family as FLJ31818, potentially enhancing its activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium concentration, thereby activating calcium-dependent proteins and signaling pathways. This can lead to the activation of proteins that are structurally or functionally similar to FLJ31818. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a polyphenol that acts as an antioxidant and also has kinase inhibitory activity. By inhibiting certain kinases, EGCG could reduce negative regulatory phosphorylations, thereby enhancing the activity of proteins including those akin to FLJ31818. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
This lipid signaling molecule activates sphingosine-1-phosphate receptors, which modulate various signaling pathways. This can lead to the activation of proteins within the same signaling cascades as FLJ31818, thereby enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that can lead to changes in the downstream AKT signaling pathway. This modulation can alter the activity of proteins that are regulated by the same pathway as FLJ31818. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 inhibits MEK1/2, which are upstream of ERK in the MAPK pathway. Inhibition of this pathway can result in the derepression of proteins regulated similarly to FLJ31818, potentially enhancing its activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 selectively inhibits p38 MAPK, which can shift signaling dynamics to favor pathways that activate proteins like FLJ31818, resulting in increased functional activity. | ||||||
FTY720 | 162359-56-0 | sc-202161 sc-202161A sc-202161B | 1 mg 5 mg 25 mg | $33.00 $77.00 $120.00 | 14 | |
FTY720 is a sphingosine-1-phosphate receptor modulator. By influencing this receptor, it can alter signaling pathways and potentially enhance the functional activity of proteins that are part of the same pathway as FLJ31818. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 is a calcium ionophore that increases intracellular calcium, which can activate calcium-dependent protein kinases that could enhance the activity of proteins structurally related to FLJ31818. | ||||||