Date published: 2025-10-21

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Fat Inhibitors

Fat inhibitors, as their name implies, are a category of compounds that interfere with the body's ability to metabolize and absorb fats. This interference can occur through a myriad of mechanisms, but the ultimate goal of these molecules is to reduce the uptake or synthesis of fats in the body. On a molecular level, fat inhibitors target specific enzymes or biochemical pathways associated with fat metabolism. For instance, some compounds in this category function by hindering the action of enzymes that break down fat molecules, while others can inhibit enzymes involved in the synthesis of fatty acids. This fascinating interaction at the microscopic scale means that these compounds influence fat levels in the broader biological system.

Diving deeper into the chemical makeup and functioning of these inhibitors, it becomes evident that they are a diverse group. They range from naturally occurring compounds, like certain plant extracts and constituents, to fully synthetic molecules engineered for specific inhibitory actions. This wide range of sources and structures means that different fat inhibitors can have varying affinities and specificities for their target molecules. The interaction between the inhibitor and its target is often governed by factors such as the compound's structure, polarity, and charge distribution. It's this intricate dance of chemical interactions and molecular affinities that enables fat inhibitors to play such a crucial role in the realm of fat metabolism. As researchers continue to delve into the complex world of these compounds, a more profound understanding of their chemical intricacies will undoubtedly emerge.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lipase Inhibitor, THL

96829-58-2sc-203108
50 mg
$51.00
7
(1)

Orlistat (THL) is a lipase inhibitor. It works by inhibiting gastric and pancreatic lipases, thus reducing the absorption of dietary fats from the intestine.

Rimonabant

168273-06-1sc-205491
sc-205491A
5 mg
10 mg
$72.00
$160.00
15
(1)

Rimonabant is a cannabinoid receptor antagonist. By blocking the CB1 cannabinoid receptor, it reduces appetite and food intake. It was withdrawn from the market due to psychiatric side effects.

Betaine

107-43-7sc-214595
sc-214595A
sc-214595B
sc-214595C
sc-214595D
sc-214595E
50 g
100 g
250 g
1 kg
2.5 kg
5 kg
$30.00
$40.00
$55.00
$160.00
$330.00
$580.00
2
(1)

Betaine is involved in the methylation of homocysteine to form methionine. This can influence lipid metabolism, although its primary function isn't as a fat inhibitor.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

The active compounds, catechins, in green tea extract can increase fat oxidation and raise metabolic rate. It's believed that they inhibit catechol-O-methyltransferase, an enzyme that degrades norepinephrine. This prolongs the action of norepinephrine and enhances fat breakdown.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
5 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine increases the release of catecholamines like adrenaline, which can boost metabolism and enhance fat breakdown. It's also a central nervous system stimulant that can increase energy expenditure.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$33.00
$63.00
$163.00
$275.00
4
(2)

CLA isomers can modulate lipid metabolism by influencing enzymes involved in the synthesis and breakdown of fatty acids, potentially leading to reduced fat storage.

Capsaicin

404-86-4sc-3577
sc-3577C
sc-3577D
sc-3577A
50 mg
250 mg
500 mg
1 g
$94.00
$173.00
$255.00
$423.00
26
(1)

Capsaicin, found in chili peppers, can increase energy expenditure and fat oxidation. It's believed to stimulate the sympathetic nervous system and increase the release of catecholamines.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine has been shown to activate AMP-activated protein kinase (AMPK), which plays a key role in regulating cellular energy homeostasis and can inhibit fat storage.

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin is found in the Coleus plant and can increase the cellular levels of cyclic AMP (cAMP). Elevated cAMP can stimulate the breakdown of stored fat in fat cells.