FASP1 Activators
The category of FASP1 Activators represents a group of chemicals known for their potential to indirectly influence the activation of FASP1 (MIS18A), a protein involved in chromatin assembly and related cellular processes. These activators exert their effects through various mechanisms, primarily targeting key cellular pathways that indirectly impact FASP1 activation. Chemicals within this class include compounds like Trichostatin A, Etoposide, Nocodazole, Puromycin, Hydroxyurea, Valproic Acid, Paclitaxel, Vorinostat, Aphidicolin, Actinomycin D, Camptothecin, and Bleomycin. Trichostatin A and Vorinostat are histone deacetylase inhibitors that modify histone acetylation patterns, potentially altering chromatin structure and indirectly activating FASP1. Etoposide, by inhibiting topoisomerase II, impacts DNA integrity, leading to changes in chromatin organization that can indirectly influence FASP1 activation.
Nocodazole disrupts microtubule dynamics, critical for proper chromosome segregation during cell division, indirectly affecting chromatin assembly processes and potentially activating FASP1. Puromycin interferes with protein synthesis, potentially reducing the availability of chromatin assembly factors and indirectly promoting FASP1 activation. Hydroxyurea inhibits ribonucleotide reductase, essential for DNA synthesis, thereby indirectly influencing chromatin assembly and FASP1 activation. Valproic Acid and Vorinostat, both histone deacetylase inhibitors, modify histone acetylation patterns, potentially affecting chromatin structure and indirectly promoting FASP1 activation. Paclitaxel stabilizes microtubules, affecting mitotic spindle formation and chromatin dynamics, indirectly influencing FASP1 activation. Aphidicolin inhibits DNA polymerases, potentially altering DNA replication dynamics and indirectly promoting FASP1 activation. Actinomycin D inhibits transcription by RNA polymerase, leading to changes in gene expression patterns that can indirectly influence various cellular processes, including chromatin assembly, and promote FASP1 activation. Camptothecin, a topoisomerase I inhibitor, impacts DNA topology, indirectly altering chromatin organization and promoting FASP1 activation. Bleomycin is a DNA-damaging agent that disrupts DNA integrity, potentially leading to changes in DNA structure and chromatin-related processes, ultimately promoting FASP1 activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A is a histone deacetylase inhibitor that modulates histone acetylation levels. Altered chromatin structure due to changes in histone acetylation may impact the availability or activity of factors that indirectly activate FASP1 (MIS18A). | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide, a topoisomerase II inhibitor, affects DNA structure. Changes in DNA integrity can influence chromatin organization and indirectly affect the activation of proteins like FASP1 (MIS18A) involved in chromatin assembly. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubule dynamics, which play a critical role in proper chromosome segregation during cell division. Disruption of microtubules can indirectly impact processes related to chromatin assembly and potentially activate FASP1 (MIS18A). | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $40.00 $210.00 $816.00 $65.00 | 394 | |
Puromycin interferes with protein synthesis. Reduced synthesis of certain proteins involved in chromatin assembly may indirectly influence the activation of FASP1 (MIS18A). | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, which is essential for DNA synthesis. Changes in DNA replication dynamics can indirectly affect chromatin assembly processes and activate FASP1 (MIS18A). | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $85.00 | 9 | |
Valproic acid, a histone deacetylase inhibitor, modifies histone acetylation patterns. Altered histone acetylation can indirectly impact chromatin organization and potentially activate FASP1 (MIS18A). | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $40.00 $73.00 $217.00 $242.00 $724.00 $1196.00 | 39 | |
Paclitaxel stabilizes microtubules, affecting mitotic spindle formation during cell division. Disrupted spindle assembly can indirectly influence chromatin dynamics and activate FASP1 (MIS18A). | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat, as a histone deacetylase inhibitor, can alter histone acetylation levels. Changes in chromatin structure due to histone modifications may indirectly activate FASP1 (MIS18A). | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $82.00 $300.00 $1082.00 | 30 | |
Aphidicolin inhibits DNA polymerases, impacting DNA replication. Altered DNA replication dynamics can indirectly affect chromatin assembly and activate FASP1 (MIS18A). | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Actinomycin D inhibits transcription by RNA polymerase. Changes in gene expression patterns can indirectly influence various cellular processes, including chromatin assembly, and activate FASP1 (MIS18A). | ||||||