FAM98C Inhibitors

FAM98C inhibitors encompass a range of compounds that influence various cellular signaling pathways and processes. LY294002 and Wortmannin are two such inhibitors that target the PI3K/AKT signaling pathway. By inhibiting PI3K, these compounds prevent the phosphorylation and subsequent activation of AKT, leading to a decrease in downstream signaling activities that may involve FAM98C. This reduced signaling can result in lower FAM98C activity if FAM98C's function is reliant on signals propagated through the AKT pathway.

In addition to the PI3K/AKT pathway, other compounds such as PD98059 and U0126 target the MAPK/ERK pathway by specifically inhibiting MEK1/2. This inhibition results in less activation of ERK, a kinase that could phosphorylate and regulate FAM98C.