FAM62B inhibitors constitute a specialized class of chemical compounds designed to specifically interfere with the function of the FAM62B protein, a protein encoded by the FAM62B gene. These inhibitors work by targeting the unique processes and pathways in which FAM62B is a critical component. FAM62B plays a role in various cellular activities, including signal transduction, cellular differentiation, or apoptosis. Consequently, the inhibitors of this protein are crafted to disrupt these specific mechanisms without affecting unrelated pathways. The inhibitors achieve this by either binding directly to the FAM62B protein, thus preventing it from interacting with other molecules essential for its activity, or by interfering with the upstream or downstream elements within the signaling cascade that FAM62B is a part of. This level of specificity ensures a targeted approach to inhibit the function of FAM62B without inducing widespread effects on the cell's overall physiology.
To create such a tailored inhibitory effect, FAM62B inhibitors might be designed to bind to the active site or other functional domains of FAM62B, which are crucial for its biological activity. Alternatively, they could act on regulatory proteins that modulate FAM62B's function, or on the substrates and products of the reactions catalyzed or facilitated by FAM62B. The precise design and function of these inhibitors depend on a deep understanding of the protein's structure and the precise biochemical pathways it is involved in. The development of FAM62B inhibitors is guided by the principle of minimal off-target activity, focusing on the highest possible inhibition of FAM62B while ensuring that other proteins and pathways remain unimpeded. As a result, these inhibitors are potent tools for research into the fundamental role of FAM62B within the cell, providing insights into the protein's involvement in cellular processes and its potential as a focal point in the complex network of intracellular signaling.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. FAM62B's activity is influenced by phosphorylation; staurosporine may reduce its activity by preventing this modification. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. Since PI3K signaling can modulate various proteins, inhibiting PI3K can indirectly decrease FAM62B's activation if FAM62B operates downstream of PI3K/Akt pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor. If FAM62B functions are downstream of mTOR signaling, rapamycin would indirectly decrease FAM62B's activity by inhibiting mTOR-dependent pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is a MEK inhibitor, which could reduce ERK pathway signaling. If FAM62B is regulated by the ERK pathway, its activity may be indirectly decreased by PD98059. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 acts as a p38 MAPK inhibitor. If FAM62B is involved in the p38 MAPK pathway, inhibiting this kinase can lead to reduced FAM62B activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of JNK. By inhibiting JNK, SP600125 can lead to decreased activity of proteins regulated by the JNK pathway, potentially including FAM62B. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $458.00 | 61 | |
BAPTA-AM is a calcium chelator, which can disrupt intracellular calcium signaling. If FAM62B is calcium-dependent, its activity could be indirectly inhibited by BAPTA-AM. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $166.00 $306.00 $1675.00 | 18 | |
W-7 Hydrochloride is a calmodulin antagonist. If FAM62B depends on calmodulin for its activation, W-7 Hydrochloride can lead to a decrease in FAM62B activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632 is a ROCK inhibitor. If FAM62B's function is associated with the Rho/ROCK pathway, inhibiting ROCK could lead to decreased activity of FAM62B. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a tyrosine kinase inhibitor. If FAM62B activity is regulated through tyrosine kinase signaling, Genistein can indirectly decrease its activation. | ||||||