FAM60A Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $47.00 $143.00 $680.00 | 16 | |
As an FGFR inhibitor, PD173074 can inhibit the fibroblast growth factor receptor pathway, which is known to be involved in the chromatin remodeling complex that FAM60A is a part of. Inhibition of FGFR would suppress the downstream signaling required for the functioning of the complex, thereby inhibiting FAM60A activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
This compound is a ROCK inhibitor, and ROCK has been implicated in numerous cellular functions including organization of the actin cytoskeleton which is essential for the nuclear architecture where FAM60A operates. Inhibition of ROCK could impair the structural integrity necessary for FAM60A to properly function within the chromatin remodeling complexes. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
By selectively inhibiting the TGF-β receptor, SB431542 can impede the TGF-β signaling pathway. TGF-β signaling is known to regulate a wide range of cellular processes including those that are related to the chromatin structure and function, therefore, inhibition could indirectly hamper FAM60A's role in chromatin remodeling. | ||||||
4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | 1062368-24-4 | sc-476297 | 5 mg | $240.00 | ||
This compound is a potent BMP pathway inhibitor, which influences the chromatin state and gene expression. As FAM60A is implicated in gene regulation via chromatin remodeling, LDN-193189 can inhibit the signaling necessary for FAM60A to exert its function on chromatin. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of c-Jun N-terminal kinase (JNK), SP600125 could disrupt the JNK signaling that may intersect with pathways governing chromatin remodeling and the cellular functions that FAM60A is involved in, leading to an inhibition of FAM60A activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
A MEK inhibitor such as U0126 can inhibit the MAPK/ERK pathway, which is involved in cell cycle control and gene expression regulation. This could indirectly inhibit the function of FAM60A within its chromatin remodeling context, as these pathways are interconnected. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
As a PI3K inhibitor, LY294002 can suppress the PI3K/AKT/mTOR signaling pathway, which has downstream effects on chromatin remodeling and gene expression where FAM60A plays a role, thereby functionally inhibiting FAM60A. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibiting mTOR with Rapamycin can lead to alterations in cellular growth and gene expression processes that are essential for the proper function of chromatin remodeling complexes involving FAM60A, thus inhibiting its activity. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
This is a histone deacetylase inhibitor that can change the chromatin state, thus potentially inhibiting the function of FAM60A by altering the chromatin landscape it acts upon. | ||||||
SGC-CBP30 | 1613695-14-9 | sc-473871 sc-473871A | 5 mg 10 mg | $178.00 $338.00 | ||
As a CREBBP/EP300 inhibitor, SGC-CBP30 can suppress the acetylation of histones, a modification that FAM60A is implicated in regulating within chromatin remodeling complexes, thereby inhibiting FAM60A's functional role. | ||||||