FAM18B2 Activators
Forskolin directly raises cyclic AMP levels, which in turn activate PKA, a kinase that can phosphorylate a wide range of substrates, including proteins and transcription factors that may be involved in the expression of FAM18B2. Epigallocatechin gallate and Resveratrol exert their influence by altering the epigenetic landscape, which can lead to changes in the expression levels of a multitude of genes, including FAM18B2. Sodium butyrate, a histone deacetylase inhibitor, can lead to chromatin remodeling, which typically results in increased gene expression.
Kinase inhibitors like LY294002, PD98059, SP600125, and SB203580 act by disrupting specific kinase-dependent signaling pathways, resulting in changes to protein function and gene expression that can impact FAM18B2. Rapamycin, a well-known inhibitor of the mTOR signaling pathway, can lead to broad changes in cellular growth and metabolism that are likely to affect the expression of FAM18B2. Genistein's role as a tyrosine kinase inhibitor suggests it can influence various pathways, with possible downstream effects on FAM18B2 expression. Dibutyryl-cAMP, a cAMP analog, and 5-Aza-2'-deoxycytidine, a DNA methyltransferase inhibitor, can also lead to changes in cell signaling and gene expression that may alter the activity of FAM18B2.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Modifies epigenetic marks, which can enhance expression of genes like FAM18B2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Influences sirtuin pathways and modifies chromatin structure, possibly affecting FAM18B2 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Inhibits histone deacetylase, leading to a relaxed chromatin structure and possibly higher FAM18B2 expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
PI3K inhibitor, can lead to alterations in cell signaling pathways, affecting FAM18B2 activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, can alter MAPK pathway signaling, potentially influencing FAM18B2 expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, which can modulate transcription factors and genes related to FAM18B2 activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor, can affect downstream targets that may influence FAM18B2 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR pathway, which can lead to changes in protein synthesis and gene expression relevant to FAM18B2. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Tyrosine kinase inhibitor, can alter various signaling pathways, possibly affecting FAM18B2. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
cAMP analog, can activate PKA and lead to changes in cellular processes impacting FAM18B2. | ||||||