FAM167A Activators
Family with sequence similarity 167 member A (FAM167A), also known by its gene symbol FAM167A, is a relatively lesser-characterized protein that belongs to a family of proteins with conserved sequence motifs. FAM167A is encoded by the FAM167A gene located on chromosome 3 in humans. The biological functions of FAM167A are not fully elucidated; however, it is thought to be involved in various cellular processes due to its widespread expression in different tissues.
Alterations in the expression or function of FAM167A have been associated with autoimmune diseases, such as systemic lupus erythematosus (SLE), indicating a possible role in the regulation of the immune system. Additionally, genetic studies have identified single nucleotide polymorphisms (SNPs) within the FAM167A gene that are linked to increased susceptibility to SLE, suggesting that FAM167A's function could be crucial for maintaining immune homeostasis.Although the exact molecular mechanisms of FAM167A action remain to be fully determined, ongoing research continues to explore its potential interactions and effects on cellular signaling pathways. Understanding the role of FAM167A in health and disease is of interest to the scientific community, as it may shed light on novel pathways affecting immune function.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein acts as a tyrosine kinase inhibitor, potentially reducing competition in signaling pathways and indirectly enhancing the activity of FAM167A. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine-1-phosphate modulates lipid signaling pathways that could influence cellular processes in which FAM167A is involved, leading to its enhanced activity. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin alters calcium signaling by blocking the sarco/endoplasmic reticulum Ca2+ ATPase, which could indirectly activate FAM167A through calcium-dependent pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC) which is involved in numerous signaling pathways, potentially leading to the enhanced activity of FAM167A. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a kinase inhibitor that may shift signaling equilibrium, possibly favoring pathways in which FAM167A is active, thus enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that could influence signaling pathways involving FAM167A, potentially leading to its enhanced activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin inhibits PI3K, altering downstream signaling that may lead to the enhanced activity of FAM167A through indirect mechanisms. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAP kinase, which could shift signaling dynamics to favor pathways that enhance FAM167A activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 inhibits MEK1/2, potentially allowing for increased activity of FAM167A through indirect modulation of signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A23187 increases intracellular calcium levels, indirectly enhancing FAM167A activity by activating related calcium-dependent signaling pathways. | ||||||