FAAH Inhibitors
Santa Cruz Biotechnology now offers a broad range of FAAH Inhibitors. FAAH is a membrane-bound enzyme fatty acid amide hydrolase responsible for the hydrolysis of multiple primary and secondary fatty acid amides, including the neuromodulatory compounds anandamine and oleamide. FAAH Inhibitors offered by Santa Cruz inhibit FAAH and, in some cases, other amidase and anandamide uptake related proteins. View detailed FAAH Inhibitor specifications, including FAAH Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 31 to 35 of 35 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
IDFP | 615250-02-7 | sc-205348 sc-205348A | 500 µg 1 mg | $90.00 $129.00 | ||
IDFP is a potent inhibitor of fatty acid amide hydrolase (FAAH), characterized by its ability to form covalent bonds with the enzyme's active site. This irreversible binding alters the enzyme's conformation, significantly affecting its catalytic efficiency. The compound's unique electrophilic nature facilitates nucleophilic attack by serine residues in FAAH, leading to a prolonged inhibition effect. This mechanism disrupts lipid metabolism, influencing various signaling pathways and cellular responses. | ||||||
JP104 | 887264-45-1 | sc-221782 sc-221782A | 5 mg 10 mg | $70.00 $135.00 | ||
JP104 acts as a selective inhibitor of fatty acid amide hydrolase (FAAH) through a unique mechanism involving the formation of a stable acyl-enzyme intermediate. Its structure allows for specific interactions with the enzyme's active site, enhancing its affinity and leading to a significant reduction in enzymatic activity. The compound's reactivity with nucleophilic residues promotes a distinct kinetic profile, resulting in a sustained modulation of lipid signaling pathways. | ||||||
Methyl α-Linolenyl Fluorophosphonate | sc-221926 sc-221926A | 1 mg 5 mg | $120.00 $350.00 | |||
Methyl α-Linolenyl Fluorophosphonate exhibits a distinctive reactivity pattern as a potent inhibitor of fatty acid amide hydrolase (FAAH). Its fluorophosphonate group facilitates the formation of a covalent bond with serine residues in the enzyme, leading to irreversible inhibition. This compound's unique steric and electronic properties enable selective targeting of FAAH, altering substrate binding dynamics and influencing lipid metabolism through prolonged enzyme modulation. | ||||||
Methyl γ-Linolenyl Fluorophosphonate | sc-221932 sc-221932A | 1 mg 5 mg | $86.00 $391.00 | |||
Methyl γ-Linolenyl Fluorophosphonate showcases remarkable specificity in its interaction with fatty acid amide hydrolase (FAAH) due to its unique γ-linolenyl structure. The compound's fluorophosphonate moiety enhances electrophilicity, promoting rapid nucleophilic attack by the enzyme's active site. This results in a stable adduct formation, effectively modulating enzyme kinetics and altering the hydrolysis of bioactive lipids, thereby impacting cellular signaling pathways. | ||||||
trans-2-(4-Biphenyl)vinylboronic acid | 352530-23-5 | sc-255669 | 1 g | $44.00 | ||
Trans-2-(4-Biphenyl)vinylboronic acid exhibits intriguing reactivity as a boronic acid derivative, particularly in its interactions with fatty acid amide hydrolase (FAAH). The presence of the biphenyl moiety enhances π-π stacking interactions, facilitating enzyme binding. Its boronic acid functionality allows for reversible covalent interactions with serine residues in the active site, influencing reaction kinetics and potentially altering substrate specificity, thereby impacting lipid metabolism pathways. | ||||||