Molecular structure of IDFP, CAS Number: 615250-02-7
IDFP (CAS 615250-02-7)
Application:
IDFP is a dual inhibitor of Monoglyceride Lipase (MAGL) and FAAH
CAS Number:
615250-02-7
Molecular Weight:
294.4
Molecular Formula:
C15H32FO2P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
An organophosphorus compound that dually inhibits MAGL and FAAH with IC50 values of 0.8 and 3 nM, respectively.1 At 10 mg/kg, IDFP elevates brain levels of 2-AG and AEA more than 10-fold, and decreases levels of arachidonic acid by 10-fold.1
IDFP (CAS 615250-02-7) References
- Activation of the endocannabinoid system by organophosphorus nerve agents. | Nomura, DK., et al. 2008. Nat Chem Biol. 4: 373-8. PMID: 18438404
- Organophosphate-sensitive lipases modulate brain lysophospholipids, ether lipids and endocannabinoids. | Casida, JE., et al. 2008. Chem Biol Interact. 175: 355-64. PMID: 18495101
- Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s). | Suzuki, H., et al. 2014. Toxicol Lett. 225: 153-7. PMID: 24361246
- Stimulation of diuresis and natriuresis by renomedullary infusion of a dual inhibitor of fatty acid amide hydrolase and monoacylglycerol lipase. | Ahmad, A., et al. 2017. Am J Physiol Renal Physiol. 313: F1068-F1076. PMID: 28768662
- Performance of the new ID-fungi plate using two types of reference libraries (Bruker and MSI) to identify fungi with the Bruker MALDI Biotyper. | Heireman, L., et al. 2020. Med Mycol. 58: 946-957. PMID: 32030423
- Evaluation of ID Fungi Plates Medium for Identification of Molds by MALDI Biotyper. | Robert, MG., et al. 2020. J Clin Microbiol. 58: PMID: 32051262
- Evaluation of the new Id-Fungi plates from Conidia for MALDI-TOF MS identification of filamentous fungi and comparison with conventional methods as identification tool for dermatophytes from nails, hair and skin samples. | Sacheli, R., et al. 2020. Mycoses. 63: 1115-1127. PMID: 32757444
- Rapid identification of fungi from respiratory samples by Bruker Biotyper matrix-assisted laser desorption/ionisation time-of-flight using ID-FUNGI plates. | Cardot Martin, E., et al. 2021. Eur J Clin Microbiol Infect Dis. 40: 391-395. PMID: 32808108
- Investigations upon the Improvement of Dermatophyte Identification Using an Online Mass Spectrometry Application. | Jabet, A., et al. 2022. J Fungi (Basel). 8: PMID: 35050013
Inhibitor of:
FAAH, and Monoglyceride Lipase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IDFP, 500 µg | sc-205348 | 500 µg | $90.00 | |||
IDFP, 1 mg | sc-205348A | 1 mg | $129.00 |