Methyl γ-Linolenyl Fluorophosphonate
Molecular Weight:
344.4
Molecular Formula:
C19H34FO2P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An analog of methyl arachidonyl fluozophosphonate (MAFP), which has been widely studied as an inhibitor of phospholipases, FAAH, and as a CB receptor ligand.1,2,3 The pharmacology of the γ-linolenyl analog of MAFP has not been completely investigated.
Methyl γ-Linolenyl Fluorophosphonate References
- Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid. | Zhang, W., et al. 2011. Proc Natl Acad Sci U S A. 108: 15757-62. PMID: 21908709
- HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms. | Emert, B., et al. 2014. J Lipid Res. 55: 1678-92. PMID: 24859737
- Structure of Human GIVD Cytosolic Phospholipase A2 Reveals Insights into Substrate Recognition. | Wang, H., et al. 2016. J Mol Biol. 428: 2769-79. PMID: 27220631
- Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate. | Lio, YC., et al. 1996. Biochim Biophys Acta. 1302: 55-60. PMID: 8695655
- Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase. | Deutsch, DG., et al. 1997. Biochem Pharmacol. 53: 255-60. PMID: 9065728
Inhibitor of:
FAAH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Methyl γ-Linolenyl Fluorophosphonate, 1 mg | sc-221932 | 1 mg | $86.00 | |||
Methyl γ-Linolenyl Fluorophosphonate, 5 mg | sc-221932A | 5 mg | $391.00 |