EPHEXIN Activators
Ephexin activators, found in its pivotal role in the ephrin signaling pathway and its identity as a guanine nucleotide exchange factor, include a variety of chemicals that touch upon a myriad of interconnected signaling pathways. Many of these chemicals, such as EGF, directly or indirectly stimulate receptor-mediated signaling events. The initiation of these signaling events can ripple through complex pathways that ultimately influence the activity of ephexin. An emphasis on the role of ephexin in cytoskeletal rearrangements is evident with chemicals like Jasplakinolide and Blebbistatin.
Furthermore, as ephexin modulates Rho GTPases, Rho-associated pathways stand out as crucial players in ephexin activation. This wide array of chemicals underscores the intricate balance and vast networking of signaling pathways that collectively converge upon, and regulate, the activity of ephexin within cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Another MEK inhibitor, possibly modulating ephexin through ERK signaling alteration. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Rho-kinase (ROCK) inhibitor, indirectly modulating ephexin by altering Rho signaling. | ||||||
Calpeptin | 117591-20-5 | sc-202516 sc-202516A | 10 mg 50 mg | $121.00 $456.00 | 28 | |
Calpain inhibitor, can impact ephexin indirectly by affecting cytoskeletal rearrangements. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Actin polymerization inducer, potentially influencing ephexin through cytoskeletal alterations. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Myosin II inhibitor, might indirectly modulate ephexin by altering actomyosin contractility. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor which can potentially affect ephexin through PI3K/Akt signaling modulation. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, raising cAMP levels, which may indirectly influence ephexin. | ||||||