ELAC2 Activators
ELAC2 activators are diverse in their chemical nature and underlying mechanisms of action. These activators work through various biochemical and cellular pathways, all of which ELAC2 is directly involved in. Dexamethasone and Rapamycin, for instance, enhance the functional activity of ELAC2 through the PI3K/AKT pathway. Tamoxifen, on the other hand, works by influencing the ER pathway, thereby enhancing the function of ELAC2.
On the other hand, Quercetin and Metformin activate the AMPK pathway, enhancing the function of ELAC2. Etoposide and Cisplatin, both known to induce DNA damage, stimulate the p53 pathway, where ELAC2 acts as a downstream effector, thus enhancing its functionality. Resveratrol, Curcumin, and Sulforaphane enhance ELAC2 activity through the SIRT1 and NRF2 pathways, respectively. Trolox, a vitamin E analogue, activates the antioxidant response element (ARE) pathway, enhancing the activity of ELAC2. Lastly, Phorbol 12-myristate 13-acetate (PMA), a PKC activator, influences the PKC pathway, leading to enhanced ELAC2 function.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
Dexamethasone is a glucocorticoid that may enhance the functional activity of ELAC2. Glucocorticoids can increase the activity of the PI3K/AKT pathway which ELAC2 is known to regulate. Through elevating the PI3K/AKT pathway, Dexamethasone enhances ELAC2 activity, leading to increased protein functionality. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a plant flavonol, is known to activate the AMPK pathway. As the ELAC2 protein plays a role in the AMPK pathway, increased activation of this pathway by Quercetin can enhance the function of ELAC2. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $51.00 $231.00 $523.00 | 63 | |
Etoposide is a topoisomerase II inhibitor that can stimulate DNA damage responses, leading to p53 activation. ELAC2, being a downstream effector of p53, can have its function enhanced by Etoposide through this pathway. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a natural phenol, activates the SIRT1 pathway. Activation of this pathway can enhance the function of ELAC2, which is known to be involved in SIRT1 mediated processes. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is a polyphenol that has been shown to activate the NRF2 pathway. ELAC2 is involved in the regulation of this pathway, and as such, Curcumin can enhance the function of ELAC2. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Tamoxifen, a selective estrogen receptor modulator, can influence the ER pathway. ELAC2, being involved in this pathway, can have its function enhanced by Tamoxifen. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin, a platinum-containing chemotherapy drug, can induce DNA damage and activate the p53 pathway. ELAC2, being a downstream effector of p53, can have its function enhanced by Cisplatin. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin, a drug used to treat type 2 diabetes, can activate the AMPK pathway. ELAC2 is involved in this pathway, and as such, Metformin can enhance the function of ELAC2. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, an isothiocyanate, can activate the NRF2 pathway. As ELAC2 is involved in the regulation of this pathway, Sulforaphane can enhance the function of ELAC2. | ||||||
Trolox | 53188-07-1 | sc-200810 sc-200810A sc-200810B sc-200810C sc-200810D | 500 mg 1 g 5 g 25 g 100 g | $38.00 $67.00 $235.00 $678.00 $1712.00 | 39 | |
Trolox is a vitamin E analogue that can activate the antioxidant response element (ARE) pathway. ELAC2 is part of this pathway, and as such, Trolox can enhance the activity of ELAC2. | ||||||