EHBP1 Activators
EHBP1 activators are chemicals that interact with various biochemical and cellular pathways to influence the activity of EH domain-binding protein 1 indirectly. This group comprises compounds that affect cyclic AMP levels, such as Forskolin and IBMX, which can modify EHBP1-mediated endocytosis via protein kinase A-dependent pathways. Agents that target the actin cytoskeleton, like Jasplakinolide and Y-27632, are crucial because EHBP1 is involved in cytoskeletal organization. By modulating the stability and dynamics of the actin network, these compounds can alter the functionality of EHBP1, enhancing its role in processes like endocytosis and cellular movement.
In addition, chemicals that interfere with GTPase activities, such as NSC23766, can impact the regulation of the actin cytoskeleton and vesicular trafficking, processes in which EHBP1 participates. By modulating GTPase signaling, these compounds can affect the interaction of EHBP1 with other proteins involved in endocytic pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, increasing cAMP levels and potentially enhancing EHBP1-mediated endocytosis through PKA-dependent signaling pathways. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
A non-selective phosphodiesterase inhibitor, raising cAMP levels, and possibly amplifying EHBP1 function by similar mechanisms as Forskolin. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, it may enhance endocytosis by modulating the actin cytoskeleton, potentially affecting EHBP1's activity. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $151.00 $609.00 | 75 | |
Rac1 inhibitor that may influence actin organization and thereby alter EHBP1's cytoskeletal association and function. | ||||||