EGFL6 Activators
EGFL6 Activators, as a chemical class, encompass a range of compounds that can influence the activity or expression of the Epidermal Growth Factor-Like Protein 6 (EGFL6).
SU5416, Sorafenib, Sunitinib, and ZD6474, for instance, are known inhibitors of VEGF receptors, a key player in angiogenesis. By modulating VEGF signaling, these compounds can indirectly affect EGFL6-associated processes in angiogenesis. Thalidomide, TNP-470, 2-Methoxyestradiol, Fumagillin, and Combretastatin A4 phosphate are other chemicals with known anti-angiogenic properties. Given the involvement of EGFL6 in angiogenesis, the action of these inhibitors can create an environment where EGFL6's activity is altered. Additionally, compounds such as Axitinib and Pazopanib target not only VEGFR but also PDGFR and c-KIT, receptors involved in cell growth and angiogenesis. Their influence on these receptors can subsequently lead to changes in cellular processes where EGFL6 is active. Everolimus, an mTOR inhibitor, offers another layer of modulation. mTOR plays a pivotal role in cellular growth, metabolism, and angiogenesis. By inhibiting this pathway, Everolimus can intersect with EGFL6's function, especially within angiogenic contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sunitinib Malate | 341031-54-7 | sc-220177 sc-220177A sc-220177B | 10 mg 100 mg 3 g | $193.00 $510.00 $1072.00 | 4 | |
Multi-targeted receptor tyrosine kinase inhibitor. By affecting angiogenesis, it may have implications for EGFL6 function. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Known to modulate angiogenic processes. It might indirectly impact pathways associated with EGFL6. | ||||||
TNP 470 | 129298-91-5 | sc-296547 | 10 mg | $230.00 | ||
An angiogenesis inhibitor. Could indirectly affect EGFL6 function within angiogenic contexts. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $70.00 $282.00 | 6 | |
A natural metabolite of estradiol that can inhibit angiogenesis and could potentially influence EGFL6-related processes. | ||||||
Fumagillin | 23110-15-8 | sc-200377 sc-200377A sc-200377B sc-200377C sc-200377D | 1 mg 5 mg 25 mg 100 mg 500 mg | $102.00 $385.00 $530.00 $1336.00 $5110.00 | 1 | |
It has anti-angiogenic properties, possibly influencing processes or pathways where EGFL6 is active. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $128.00 $638.00 | 7 | |
mTOR inhibitor, which plays a role in angiogenesis. By modulating this pathway, it might influence processes associated with EGFL6. | ||||||