Date published: 2026-5-28

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ECE Inhibitors

Santa Cruz Biotechnology now offers a broad range of ECE Inhibitors for use in various applications. ECE inhibitors, which target endothelin-converting enzymes, play a pivotal role in the research of molecular mechanisms underlying the regulation of endothelin peptide processing. These enzymes are key in the conversion of big endothelin to endothelin, peptides that are crucial for vascular functions and have profound effects on smooth muscle cells. By studying ECE inhibitors, researchers can dissect the complex pathways of endothelin activity, providing insights into their role in vascular remodeling and regulation of blood flow. These inhibitors are crucial in basic cardiovascular research, aiding in the understanding of the molecular basis of blood pressure regulation and vascular health. In molecular biology, they offer tools to manipulate endothelin levels and observe the resultant effects on cell signaling and function, which is vital for studies on cellular responses to oxidative stress and mechanical forces. Furthermore, ECE inhibitors serve as important reagents in studies investigating the interplay between vascular function and other regulatory systems such as the renal and respiratory systems. Beyond cardiovascular research, they are used in studies focusing on tissue engineering and regenerative medicine, where understanding endothelin's role in angiogenesis and tissue repair is essential. These applications underscore the broad utility of ECE inhibitors in advancing scientific understanding across various fields of life sciences. View detailed information on our available ECE Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Phosphoramidon

119942-99-3sc-201283
sc-201283A
5 mg
25 mg
$199.00
$632.00
8
(1)

Phosphoramidon is a potent inhibitor of metalloproteinases, characterized by its ability to form stable complexes with zinc ions in the active sites of these enzymes. This interaction alters the enzyme's catalytic efficiency, leading to a significant decrease in substrate turnover. The compound's unique structure allows for specific binding, influencing the kinetics of proteolytic reactions and modulating extracellular matrix remodeling processes. Its selectivity highlights its role in regulating protease activity.

CGS 35066

261619-50-5sc-203546
1 mg
$250.00
(0)

CGS 35066 is an acid halide that exhibits unique reactivity through its electrophilic carbonyl group, which readily engages in nucleophilic acyl substitution reactions. This compound demonstrates a propensity for selective acylation, influencing the reactivity of various nucleophiles. Its steric and electronic properties facilitate distinct reaction pathways, leading to the formation of diverse derivatives. The compound's stability under specific conditions allows for controlled reactivity, making it a versatile intermediate in synthetic applications.

SM-19712

194542-56-8sc-215859
sc-215859A
5 mg
25 mg
$235.00
$869.00
(0)

SM-19712 is an acid halide characterized by its highly reactive acyl chloride functionality, which promotes rapid acylation reactions with nucleophiles. Its unique steric environment enhances selectivity, allowing for regio- and stereoselective transformations. The compound's ability to form stable intermediates during reaction kinetics enables efficient synthesis pathways. Additionally, its solubility properties facilitate interactions with various solvents, influencing reaction dynamics and product formation.