Molecular structure of CGS 35066, CAS Number: 261619-50-5
CGS 35066 (CAS 261619-50-5)
Alternate Names:
α-[(S)-(Phosphonomethyl)amino]-3-dibenzofuranpropanoic acid
Application:
CGS 35066 is a potent endothelin-converting enzyme (ECE) inhibitor
CAS Number:
261619-50-5
Purity:
>98%
Molecular Weight:
349.28
Molecular Formula:
C16H16NO6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Potent endothelin-converting enzyme (ECE) inhibitor that displays > 100-fold selectivity over neutral endopeptidase 24.11 (IC50 values are 22 and 2300 nM respectively). Blocks the hypertensive effects induced by big ET-1 in vitro and reduces the magnitude of cerebral vasospasm following subarachnoid hemorrhage (SAH).
CGS 35066 (CAS 261619-50-5) References
De Lombaert et al (2000) Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action. J.Med.Chem. 43 488. Trapani et al (2000) Pharmacological properties of CGS 35066, a potent and selective endothelin-Inhibitor of:
ECE.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CGS 35066, 1 mg | sc-203546 | 1 mg | $250.00 |