Date published: 2026-3-7

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ECE-1 Antibodies

Santa Cruz Biotechnology offers a broad range of ECE-1 monoclonal antibodies for research focused on understanding endothelin-converting enzyme 1. ECE-1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Endothelin-converting enzyme 1 is crucial for the conversion of big endothelin-1 to its active form, playing a significant role in regulating vascular tone and blood pressure. Dysregulation of ECE-1 has been implicated in various cardiovascular diseases, making it an important target for therapeutic intervention. Understanding ECE-1 function can provide insights into the mechanisms underlying cardiovascular conditions and aid in the development of new treatment strategies. ECE-1 research continues to reveal new pathways and mechanisms in cardiovascular biology. Investigating ECE-1 expression patterns helps researchers better understand vascular system regulation. Current studies focusing on ECE-1 are uncovering potential therapeutic approaches for cardiovascular disorders. Santa Cruz Biotechnology monoclonal antibodies for ECE-1 enable researchers worldwide to advance scientific understanding of cardiovascular health and disease.

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ECE-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ECE-1 Antibody (A-6)

sc-376017mouse IgG1 κ331-390 (h)WB, IP, IF, ELISAm, r, h
5
(2)

ECE-1 Antibody (C-12)

sc-376018mouse IgG2a κ331-390 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(2)

ECE-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ECE-1 Double Nickase Plasmid (h)

sc-402379-NIChGene KnockoutPuromycin0
(0)

ECE-1 Double Nickase Plasmid (h2)

sc-402379-NIC-2hGene KnockoutPuromycin0
(0)

ECE-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ECE-1 siRNA (h)

sc-44478hGene SilencingN/A
1
(0)

ECE-1 shRNA Plasmid (h)

sc-44478-SHhGene SilencingPuromycin
1
(0)

ECE-1 shRNA (h) Lentiviral Particles

sc-44478-VhGene SilencingPuromycin
1
(0)

ECE-1 siRNA (m)

sc-44479mGene SilencingN/A0
(0)

ECE-1 shRNA Plasmid (m)

sc-44479-SHmGene SilencingPuromycin0
(0)

ECE-1 shRNA (m) Lentiviral Particles

sc-44479-VmGene SilencingPuromycin0
(0)