EAPP inhibitors pertain to a distinct category of chemical compounds developed to interact with and regulate the activity of the EAPP protein, which stands for E2F-associated phosphoprotein. EAPP is a multifunctional protein involved in various cellular processes, including cell cycle regulation, transcriptional control, and DNA repair. These inhibitors are designed to engage with specific regions or binding sites on the EAPP protein, potentially influencing its interactions with other cellular components, cellular localization, or participation in various cellular processes where EAPP plays a role.
Structurally, EAPP inhibitors are carefully crafted to facilitate binding with EAPP, thereby affecting its functions within the cell. The exact mechanisms through which EAPP inhibitors exert their effects can vary and are typically a subject of ongoing scientific investigation. Researchers use these inhibitors as valuable tools to dissect the roles of EAPP in the intricate machinery of the cell. By studying how EAPP is modulated by inhibitors, scientists can gain insights into the regulation of critical cellular processes like cell division, gene expression, and DNA repair. This, in turn, contributes to a deeper understanding of fundamental molecular mechanisms governing cellular homeostasis and response to various cellular stresses. Research involving EAPP inhibitors has the potential to unlock new knowledge about the underlying mechanisms of cell cycle regulation, transcriptional control, and DNA repair. Additionally, it can provide insights into how disruptions in these processes may contribute to diseases such as cancer, where abnormal cell proliferation and genomic instability are common features.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Sirolimus targets mTOR and can influence cell cycle progression. By modulating the cell cycle, it might indirectly affect EAPP expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
As a PI3K inhibitor, LY294002 affects many cellular processes including cell cycle, potentially impacting EAPP expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor, and by influencing the MAPK pathway, it might have an indirect effect on EAPP levels. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
This JNK inhibitor might influence the cell cycle and thereby potentially affect EAPP expression. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
This NF-kB pathway inhibitor can affect various cellular processes, including cell cycle, potentially impacting EAPP expression. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $150.00 $349.00 | 15 | |
Aurora kinase inhibitor that affects cell cycle progression and could influence EAPP expression. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can modulate cell cycle progression, potentially affecting EAPP levels. | ||||||
MLN8237 | 1028486-01-2 | sc-394162 | 5 mg | $220.00 | ||
Inhibits Aurora A kinase, impacting cell cycle and possibly EAPP expression. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Nocodazole disrupts microtubules and arrests cells in mitosis, potentially influencing EAPP. | ||||||