Date published: 2026-4-24

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EAPP Activators

EAPP Activators refer to a class of chemical compounds that are designed to boost the expression or activity of E2F-associated phosphoprotein (EAPP), a protein encoded by the C6orf166 gene in humans. This protein is a critical participant in the cell cycle regulation, acting as a link between the E2F transcription factor and the cyclin A-associated kinase, contributing to the transition from the G1 to the S phase of the cell cycle. Therefore, EAPP activators, through their inherent chemistry and mechanisms, can influence these fundamental cellular processes by modulating the expression or functionality of EAPP.

EAPP activators can operate in a variety of ways. Some may interact directly with the EAPP protein or its encoding gene, boosting its expression or its ability to interact with other proteins. Others might function by targeting the signaling pathways that regulate EAPP's expression or activity, thereby enhancing its role in the cell cycle. The precise mechanisms of action for these activators can vary widely, as can their impact on the cell cycle, depending on numerous factors such as the specific compound, the cell type, and the cellular context. Despite these variations, EAPP activators represent a valuable tool for exploring the intricate processes of cell cycle regulation and the role of EAPP within that context. These compounds are instrumental in advancing our understanding of cellular biology and the complex network of interactions that govern cell proliferation and cycle progression.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rottlerin

82-08-6sc-3550
sc-3550B
sc-3550A
sc-3550C
sc-3550D
sc-3550E
10 mg
25 mg
50 mg
1 g
5 g
20 g
$84.00
$166.00
$302.00
$2091.00
$5212.00
$16657.00
51
(2)

Rottlerin is known to inhibit the protein kinase C delta (PKCδ) which may impact cell cycle regulation and potentially influence EAPP expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can regulate gene expression through modulation of transcription factors like NF-κB, which may indirectly affect EAPP expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein is a tyrosine kinase inhibitor that can impact cell cycle regulation and potentially influence EAPP expression.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol may alter the expression of cell cycle-related genes, possibly including EAPP, through its action on various signaling pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin can influence the cell cycle and apoptosis through various pathways, potentially impacting EAPP expression.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$51.00
$231.00
$523.00
63
(1)

Etoposide affects the cell cycle regulation by inhibiting topoisomerase II, potentially influencing EAPP expression.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

Sulforaphane can modulate gene expression in the cell cycle, potentially affecting EAPP expression.

Taxol

33069-62-4sc-201439D
sc-201439
sc-201439A
sc-201439E
sc-201439B
sc-201439C
1 mg
5 mg
25 mg
100 mg
250 mg
1 g
$41.00
$74.00
$221.00
$247.00
$738.00
$1220.00
39
(2)

Paclitaxel affects cell cycle progression by stabilizing microtubules, potentially influencing EAPP expression.