Dynlt1b Activators
Dynlt1b Activators represent a group of chemical compounds that directly or indirectly enhance the functional activity of the Dynlt1b protein. This is primarily achieved through their actions on microtubules, with which Dynlt1b interacts. Several Dynlt1b activators influence microtubule dynamics, either by stabilizing microtubules (Paclitaxel, Taxol, Epothilone B), inhibiting their polymerization (Colchicine, Vinblastine, Nocodazole, Podophyllotoxin, Maytansine), or disrupting their function (Griseofulvin). These actions increase the structures or subunits that Dynlt1b interacts with, therefore enhancing its functional activity.
Additionally, Tubacin, a histone deacetylase inhibitor, enhances Dynlt1b activity by increasing the acetylation levels of α-tubulin, a protein that forms microtubules and that Dynlt1b binds to. Similarly, Estramustine, a derivative of estradiol, binds to microtubule-associated proteins (MAPs), inhibiting microtubule dynamics and thus affecting the structures with which Dynlt1b interacts. Combretastatin A4, a tubulin depolymerizing agent, can enhance Dynlt1b activity by increasing the pool of tubulin subunits available for Dynlt1b to interact with. These chemical compounds, by specifically targeting cellular processes and pathways directly related to Dynlt1b function, provide a range of mechanisms to enhance its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tris Buffered Saline: 1 L of 1X | sc-362185 | 1 L | $21.00 | 3 | ||
Tubacin is a histone deacetylase inhibitor known to increase acetylation levels of α-tubulin, a protein that forms microtubules. Dynlt1b binds to microtubules, suggesting that Tubacin might indirectly enhance Dynlt1b activity by increasing the acetylation levels of α-tubulin. | ||||||
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and prevents their disassembly, enhancing the stability of the structures that Dynlt1b interacts with, and therefore enhancing the functional activity of Dynlt1b. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine binds to tubulin, inhibiting microtubule polymerization. This disruption of microtubule dynamics can enhance Dynlt1b activity by increasing its association with tubulin subunits. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B enhances microtubule assembly and inhibits their disassembly, thus increasing the structures that Dynlt1b interacts with and potentially enhancing its functional activity. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Podophyllotoxin inhibits microtubule assembly. As a result, it increases the pool of tubulin subunits available for Dynlt1b to interact with, potentially enhancing its functional activity. | ||||||
Estramustine | 2998-57-4 | sc-353281 sc-353281A | 100 mg 1 g | $265.00 $743.00 | ||
Estramustine is a derivative of estradiol and binds to microtubule-associated proteins (MAPs), inhibiting microtubule dynamics. This action can enhance Dynlt1b activity by affecting the structures it interacts with. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Griseofulvin disrupts microtubule function by interacting with polymerized microtubules. This can enhance Dynlt1b activity by affecting the structures it interacts with. | ||||||
Maytansine | 35846-53-8 | sc-507510 | 100 mg | $1000.00 | ||
Maytansine inhibits microtubule assembly, increasing the pool of tubulin subunits available for Dynlt1b to interact with and potentially enhancing its functional activity. | ||||||