Drac1/2 Activators
Drac1/2 activators form a diverse class of chemicals that modulate the activities of Drac1 and Drac2, members of the Rho GTPase family involved in the regulation of cellular processes. These activators include compounds targeting Rac1, Cdc42, and related signaling pathways, influencing Drac1/2 indirectly. EHop-016 and NSC23766, both Rac1 inhibitors, directly target Rac1, impeding its activity and suppressing downstream signaling. Inhibition of Rac1 by EHop-016 and NSC23766 indirectly activates Drac1/2, given their functional overlap in signaling cascades.
On the other hand, compounds like Casin act as Rac1 and Cdc42 activators, respectively. Casin, a Cdc42 activator, directly promotes the activation of Cdc42, impacting cellular processes governed by Cdc42 and indirectly influencing Drac1/2 activities. In summary, Drac1/2 activators exhibit diverse mechanisms, targeting key regulators such as Rac1 and Cdc42, and influencing their shared signaling pathways. Understanding these activators provides valuable insights into the intricate regulatory network governing Drac1/2-mediated cellular processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
EHop-016 | 1380432-32-5 | sc-497382 | 5 mg | $80.00 | ||
EHop-016, a Rac1 inhibitor, directly targets Rac1, inhibiting its activity and suppressing downstream signaling. By impeding Rac1, EHop-016 interferes with the modulation of cellular processes governed by Rac1, indirectly leading to the activation of Drac1/2, as Rac1 is a closely related member of the Rho GTPase family. | ||||||
CASIN | 425399-05-9 | sc-397016 | 10 mg | $460.00 | 1 | |
CASIN, a Cdc42 activator, directly promotes the activation of Cdc42. As Cdc42 and Drac1/2 share common signaling pathways, the activation of Cdc42 by CASIN can indirectly lead to the activation of Drac1/2, contributing to the modulation of Drac1/2-associated cellular responses. | ||||||