Date published: 2026-2-3

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DR CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. DR gene silencers are available as DR CRISPR/Cas9 Knockout plasmids and DR Double Nickase Plasmids. DR CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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DR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR4 CRISPR/Cas9 KO Plasmid (h)

sc-400747hGene KnockoutGFP0
(0)

DR4 HDR Plasmid (h)

sc-400747-HDRhHomology Directed RepairPuromycin0
(0)

DR4 Double Nickase Plasmid (h)

sc-400747-NIChGene KnockoutPuromycin0
(0)

DR4 Double Nickase Plasmid (h2)

sc-400747-NIC-2hGene KnockoutPuromycin0
(0)

DR5 CRISPR/Cas9 KO Plasmid (h)

sc-401002hGene KnockoutGFP
1
(0)

DR5 HDR Plasmid (h)

sc-401002-HDRhHomology Directed RepairPuromycin
1
(0)

DR5 Double Nickase Plasmid (h)

sc-401002-NIChGene KnockoutPuromycin
1
(0)

DR5 Double Nickase Plasmid (h2)

sc-401002-NIC-2hGene KnockoutPuromycin
1
(0)

DR5 CRISPR/Cas9 KO Plasmid (m2)

sc-423438-KO-2m2Gene KnockoutGFP0
(0)

DR5 HDR Plasmid (m2)

sc-423438-HDR-2mHomology Directed RepairPuromycin0
(0)

DR5 Double Nickase Plasmid (m)

sc-423438-NICmGene KnockoutPuromycin0
(0)

DR6 CRISPR/Cas9 KO Plasmid (m)

sc-430122mGene KnockoutGFP0
(0)

DR6 HDR Plasmid (m)

sc-430122-HDRmHomology Directed RepairPuromycin0
(0)

DR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR3 CRISPR Activation Plasmid (h)

sc-403461-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR4 CRISPR Activation Plasmid (h)

sc-400747-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR5 CRISPR Activation Plasmid (h)

sc-401002-ACThGene ActivationPuro, Blast, Hygro
1
(0)

DR6 CRISPR Activation Plasmid (h)

sc-402038-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR6 CRISPR Activation Plasmid (h2)

sc-402038-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)