Date published: 2026-5-21

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DP2 Activators

Santa Cruz Biotechnology now offers a broad range of DP2 Activators for use in various applications. DP2, also known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), is a G protein-coupled receptor involved in the immune response, particularly in the recruitment and activation of eosinophils, basophils, and Th2 cells, which are critical in allergic inflammation and asthma. DP2 Activators are essential tools in scientific research, enabling researchers to explore the specific mechanisms by which this receptor influences immune cell signaling and function. By activating DP2, scientists can investigate how this receptor modulates inflammatory pathways, contributes to the immune response, and impacts the development and exacerbation of allergic diseases. These activators are widely used in studies focused on understanding the role of DP2 in immune regulation, as well as in research exploring the potential of targeting this receptor for interventions in conditions such as asthma, allergic rhinitis, and other Th2-mediated disorders. Additionally, DP2 Activators are valuable in experiments designed to study the interplay between DP2 and other signaling pathways, providing insights into the complex regulatory networks that govern immune responses and inflammation. The availability of these activators has significantly advanced research in immunology and cell biology, offering essential tools for dissecting the intricate dynamics of immune receptor signaling and their broader implications in health and disease. View detailed information on our available DP2 Activators by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

PGD2 (Prostaglandin D2)

41598-07-6sc-201221
sc-201221A
1 mg
10 mg
$96.00
$583.00
4
(1)

Prostaglandin D2 (PGD2) serves as a potent ligand for the DP2 receptor, exhibiting a unique affinity that triggers specific intracellular signaling cascades. Its structure allows for effective hydrogen bonding and hydrophobic interactions, enhancing receptor activation. PGD2's role in modulating immune responses is underscored by its ability to influence cytokine release and cell migration. Additionally, its rapid metabolism and degradation pathways contribute to its transient biological effects, shaping physiological responses.

15(R)-15-methyl Prostaglandin D2

210978-26-0sc-223169
sc-223169A
500 µg
1 mg
$72.00
$124.00
(0)

15(R)-15-methyl Prostaglandin D2 is a selective agonist for the DP2 receptor, characterized by its unique stereochemistry that enhances receptor binding affinity. This compound engages in specific molecular interactions, promoting distinct signaling pathways that influence cellular behavior. Its structural modifications lead to altered reaction kinetics, resulting in a unique profile of biological activity. The compound's stability and metabolic pathways further define its role in modulating various physiological processes.

15(R)-Prostaglandin D2

59894-05-2sc-220629
sc-220629A
1 mg
5 mg
$120.00
$540.00
(0)

15(R)-Prostaglandin D2 is a potent ligand for the DP2 receptor, distinguished by its unique stereochemical configuration that optimizes receptor engagement. This compound initiates specific downstream signaling cascades, influencing cellular responses through selective activation. Its unique structural features contribute to differential binding dynamics and modulation of enzymatic activity, impacting the overall kinetics of receptor-mediated processes. Additionally, its metabolic stability plays a crucial role in determining its physiological effects.