Date published: 2025-12-8

1-800-457-3801

SCBT Portrait Logo
Seach Input

DISC Antibodies

Santa Cruz Biotechnology provides a broad selection of DISC Antibodies for targeting DISC (Death-Inducing Signaling Complex) proteins. DISC Antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The DISC plays a crucial role in mediating apoptosis, serving as a platform for the assembly of signaling molecules that trigger cell death in response to specific stimuli. Understanding DISC protein function is essential for elucidating the mechanisms of programmed cell death, which has significant implications in cancer research and therapeutic development. By studying the interactions and pathways involving DISC proteins, researchers can gain insights into disease progression and potential treatment strategies. DISC proteins are fundamental components in cell death signaling cascades, and their proper characterization is vital for advancing our understanding of cellular homeostasis. Investigating DIsc-mediated pathways can reveal new therapeutic targets for diseases involving dysregulated apoptosis. The high-quality monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to conduct precise investigations of DISC proteins, contributing to meaningful discoveries in cell death research and therapeutic development.

SEE ALSO...

DISC Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DISC-1 Antibody (B-2)

sc-365591mouse IgG2a κ601-810 (h)WB, IP, IF, ELISAm, r, h
5
(8)

DISC CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DISC-1 CRISPR/Cas9 KO Plasmid (h2)

sc-404052-KO-2hGene KnockoutGFP0
(0)

DISC-1 HDR Plasmid (h2)

sc-404052-HDR-2hHomology Directed RepairPuromycin0
(0)

DISC-1 Double Nickase Plasmid (h)

sc-404052-NIChGene KnockoutPuromycin0
(0)

DISC-1 Double Nickase Plasmid (h2)

sc-404052-NIC-2hGene KnockoutPuromycin0
(0)

DISC-1 CRISPR/Cas9 KO Plasmid (m)

sc-434087mGene KnockoutGFP0
(0)

DISC-1 HDR Plasmid (m)

sc-434087-HDRmHomology Directed RepairPuromycin0
(0)

DISC-1 Double Nickase Plasmid (m)

sc-434087-NICmGene KnockoutPuromycin0
(0)

DISC-1 Double Nickase Plasmid (m2)

sc-434087-NIC-2mGene KnockoutPuromycin0
(0)

DISC CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DISC-1 CRISPR Activation Plasmid (h)

sc-404052-ACThGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 CRISPR Activation Plasmid (h2)

sc-404052-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 Lentiviral Activation Particles (h)

sc-404052-LAChGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 Lentiviral Activation Particles (h2)

sc-404052-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 CRISPR Activation Plasmid (m)

sc-434087-ACTmGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 CRISPR Activation Plasmid (m2)

sc-434087-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 Lentiviral Activation Particles (m)

sc-434087-LACmGene ActivationPuro, Blast, Hygro0
(0)

DISC-1 Lentiviral Activation Particles (m2)

sc-434087-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

DISC siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DISC-1 siRNA (h)

sc-60539hGene SilencingN/A
2
(0)

DISC-1 shRNA Plasmid (h)

sc-60539-SHhGene SilencingPuromycin
2
(0)

DISC-1 shRNA (h) Lentiviral Particles

sc-60539-VhGene SilencingPuromycin
2
(0)

DISC-1 siRNA (m)

sc-60540mGene SilencingN/A0
(0)

DISC-1 shRNA Plasmid (m)

sc-60540-SHmGene SilencingPuromycin0
(0)

DISC-1 shRNA (m) Lentiviral Particles

sc-60540-VmGene SilencingPuromycin0
(0)

DISC-1 siRNA (r)

sc-106989rGene SilencingN/A0
(0)

DISC-1 shRNA Plasmid (r)

sc-106989-SHrGene SilencingPuromycin0
(0)

DISC-1 shRNA (r) Lentiviral Particles

sc-106989-VrGene SilencingPuromycin0
(0)