Date published: 2026-1-21

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DHCR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DHCR Antibodies for research in cholesterol biosynthesis and related pathways. DHCR Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DHCR, or 24-dehydrocholesterol reductase, catalyzes the final step of cholesterol synthesis by converting 24-dehydrocholesterol to cholesterol. DHCR maintains cellular membrane integrity and fluidity, while its dysregulation contributes to several diseases, including Smith-Lemli-Opitz syndrome and neurodegenerative disorders. Understanding DHCR function and regulation provides insights into cholesterol-related pathologies. Researchers worldwide rely on DHCR monoclonal antibodies to advance their studies in membrane biology and disease mechanisms. DHCR research continues to reveal new aspects of cholesterol metabolism and its impact on human health. Santa Cruz Biotechnology monoclonal antibodies enable researchers to make meaningful contributions to understanding cholesterol-related diseases.

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DHCR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DHCR24 Antibody (A-4)

sc-398938mouse IgG2b κ145-166 (h)WB, IP, IF, IHC(P), ELISAm, r, h

new

(3)

DHCR24 Antibody (D-10)

sc-390037mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
2
(4)

DHCR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DHCR7 CRISPR/Cas9 KO Plasmid (h)

sc-410538hGene KnockoutGFP0
(0)

DHCR7 HDR Plasmid (h)

sc-410538-HDRhHomology Directed RepairPuromycin0
(0)

DHCR7 CRISPR/Cas9 KO Plasmid (m)

sc-419997mGene KnockoutGFP0
(0)

DHCR7 HDR Plasmid (m)

sc-419997-HDRmHomology Directed RepairPuromycin0
(0)

DHCR7 Double Nickase Plasmid (m)

sc-419997-NICmGene KnockoutPuromycin0
(0)

DHCR7 Double Nickase Plasmid (m2)

sc-419997-NIC-2mGene KnockoutPuromycin0
(0)

DHCR24 CRISPR/Cas9 KO Plasmid (h)

sc-405507hGene KnockoutGFP0
(0)

DHCR24 HDR Plasmid (h)

sc-405507-HDRhHomology Directed RepairPuromycin0
(0)

DHCR24 Double Nickase Plasmid (h)

sc-405507-NIChGene KnockoutPuromycin0
(0)

DHCR24 Double Nickase Plasmid (h2)

sc-405507-NIC-2hGene KnockoutPuromycin0
(0)

DHCR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DHCR7 siRNA (h)

sc-60533hGene SilencingN/A
1
(0)

DHCR7 shRNA Plasmid (h)

sc-60533-SHhGene SilencingPuromycin
1
(0)

DHCR7 shRNA (h) Lentiviral Particles

sc-60533-VhGene SilencingPuromycin
1
(0)

DHCR7 siRNA (m)

sc-60534mGene SilencingN/A0
(0)

DHCR7 shRNA Plasmid (m)

sc-60534-SHmGene SilencingPuromycin0
(0)

DHCR7 shRNA (m) Lentiviral Particles

sc-60534-VmGene SilencingPuromycin0
(0)

DHCR24 siRNA (h)

sc-60531hGene SilencingN/A
2
(0)

DHCR24 shRNA Plasmid (h)

sc-60531-SHhGene SilencingPuromycin
2
(0)

DHCR24 shRNA (h) Lentiviral Particles

sc-60531-VhGene SilencingPuromycin
2
(0)

DHCR24 siRNA (m)

sc-60532mGene SilencingN/A0
(0)

DHCR24 shRNA Plasmid (m)

sc-60532-SHmGene SilencingPuromycin0
(0)

DHCR24 shRNA (m) Lentiviral Particles

sc-60532-VmGene SilencingPuromycin0
(0)