Derlin Antibodies

Santa Cruz Biotechnology features a diverse variety of Derlin monoclonal antibodies for investigating Derlin proteins in cellular processes. Derlin Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Derlin proteins are integral to the endoplasmic reticulum-associated degradation (ERAD) pathway, playing a crucial role in the quality control of protein folding and degradation. By facilitating the retrotranslocation of misfolded proteins from the endoplasmic reticulum to the cytosol, Derlin proteins help maintain cellular homeostasis and prevent the accumulation of toxic proteins. The significance of Derlin proteins extends to various physiological processes, including immune response and cellular stress management. Understanding Derlin protein function has important implications for research in neurodegenerative disorders, cancer biology, and cellular stress responses. Researchers can utilize specific monoclonal antibodies to examine protein-protein interactions and cellular localization patterns of Derlin proteins. Advanced research techniques supported by Santa Cruz Biotechnology monoclonal antibodies enable scientists to make meaningful contributions to understanding protein quality control mechanisms and their impact on human health.