Date published: 2025-10-17

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Derivatization Agents

Santa Cruz Biotechnology now offers a broad range of derivatization agents for use in various applications. Derivatization agents are critical compounds used to chemically modify analytes to enhance their detectability, stability, and chromatographic properties in analytical chemistry. These agents play a crucial role in techniques such as gas chromatography (GC), liquid chromatography (LC), and mass spectrometry (MS), where they help in converting non-volatile, thermally labile, or otherwise undetectable compounds into more amenable forms. Researchers utilize derivatization agents to improve the separation and detection of complex mixtures, enabling precise and accurate analysis of components at trace levels. In scientific research, these agents are employed to study a wide array of substances, including environmental pollutants, food additives and biological molecules. Derivatization can aid in the identification and quantification of amino acids, fatty acids, carbohydrates, and steroids, among others, by enhancing their chromatographic and spectrometric responses. By offering a comprehensive selection of high-quality derivatization agents, Santa Cruz Biotechnology supports advanced research and analytical methodologies across various fields, including biochemistry, environmental science, and forensic analysis. These agents empower scientists to achieve greater sensitivity and specificity in their analytical procedures, driving forward discoveries and innovations in their respective disciplines. View detailed information on our available derivatization agents by clicking on the product name.

Items 231 to 240 of 257 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Bromo Brassinin

1076199-55-7sc-207004
sc-207004A
sc-207004B
10 mg
100 mg
1 g
$262.00
$3264.00
$24480.00
1
(0)

5-Bromo Brassinin serves as a versatile derivatization agent, characterized by its ability to form stable covalent bonds through electrophilic interactions. Its unique bromine substituent enhances reactivity, facilitating selective modifications of functional groups. The compound's distinct steric and electronic properties influence reaction pathways, allowing for tailored derivatization strategies. Additionally, its solubility in various solvents aids in optimizing reaction conditions, making it effective for diverse analytical applications.

Lysinonorleucine

25612-46-8sc-207837
5 mg
$337.00
2
(1)

Lysinonorleucine acts as a potent derivatization agent, notable for its ability to engage in nucleophilic addition reactions due to its unique structural features. The compound's specific amino acid configuration allows for selective targeting of carbonyl groups, enhancing the formation of stable derivatives. Its reactivity is influenced by steric hindrance and electronic effects, which can be fine-tuned to optimize reaction kinetics. Furthermore, its solubility profile supports diverse analytical methodologies, enabling effective sample preparation and analysis.

2-Fluorophenylacetic acid

451-82-1sc-254252
10 g
$48.00
(0)

2-Fluorophenylacetic acid serves as an effective derivatization agent, characterized by its ability to form stable esters and amides through acylation reactions. The presence of the fluorine atom enhances electrophilicity, facilitating nucleophilic attack by amines and alcohols. Its unique aromatic structure promotes π-π stacking interactions, which can influence reaction selectivity and kinetics. Additionally, its moderate polarity aids in solubility, making it suitable for various analytical techniques.

(S)-(+)-2-Octanol

6169-06-8sc-250941
sc-250941A
5 g
10 g
$121.00
$298.00
(0)

(S)-(+)-2-Octanol acts as a versatile derivatization agent, notable for its chiral nature, which allows for the selective formation of esters and ethers. Its hydrophobic alkyl chain enhances solubility in organic solvents, promoting efficient reactions with nucleophiles. The secondary alcohol functionality enables hydrogen bonding, influencing reaction pathways and kinetics. This compound's unique stereochemistry can also impact the selectivity of reactions, making it valuable in various analytical applications.

(S)-NIFE

328406-65-1sc-253524
sc-253524A
sc-253524B
sc-253524C
sc-253524D
25 mg
250 mg
500 mg
1 g
5 g
$270.00
$1224.00
$2040.00
$3570.00
$11730.00
8
(1)

(S)-NIFE serves as a potent derivatization agent, characterized by its ability to form stable adducts through specific molecular interactions. Its unique structure facilitates the formation of amides and esters, enhancing the reactivity of functional groups. The presence of a chiral center allows for enantioselective reactions, while its polar characteristics promote solubility in various solvents. This compound's reactivity profile is influenced by steric and electronic factors, optimizing reaction kinetics for diverse applications.

3-Bromomethyl-7-methoxy-1,4-benzoxazin-2-one

124522-09-4sc-209554
100 mg
$192.00
(0)

3-Bromomethyl-7-methoxy-1,4-benzoxazin-2-one acts as a versatile derivatization agent, notable for its electrophilic bromomethyl group that readily engages in nucleophilic substitution reactions. This compound's unique benzoxazine framework enhances its stability and reactivity, allowing for selective modifications of functional groups. Its ability to form covalent bonds with nucleophiles is influenced by steric hindrance and electronic effects, making it suitable for diverse synthetic pathways.

Pentafluorophenyl acetate

19220-93-0sc-215689
sc-215689A
sc-215689B
sc-215689C
sc-215689D
500 mg
1 g
5 g
10 g
25 g
$60.00
$100.00
$340.00
$583.00
$1163.00
(0)

Pentafluorophenyl acetate serves as a powerful derivatization agent, characterized by its highly electronegative fluorine atoms that enhance electrophilicity. This compound facilitates acylation reactions, promoting the formation of stable esters through its reactive acetate moiety. The presence of multiple fluorine substituents not only increases the compound's lipophilicity but also influences reaction kinetics, allowing for rapid and selective modifications of various nucleophiles. Its unique electronic properties enable precise control over reaction conditions, making it a valuable tool in synthetic chemistry.

9-Fluorenylmethyl carbazate

35661-51-9sc-210709
250 mg
$120.00
(0)

9-Fluorenylmethyl carbazate acts as an effective derivatization agent, distinguished by its unique structural framework that enhances reactivity through π-π stacking interactions. This compound promotes the formation of stable carbazate derivatives, facilitating selective modifications of carbonyl compounds. Its robust aromatic system contributes to increased stability and solubility in organic solvents, while its ability to form hydrogen bonds allows for fine-tuning of reaction conditions, optimizing yields in synthetic applications.

Coumarin-6-sulfonyl chloride

10543-42-7sc-214771
10 mg
$30.00
(0)

Coumarin-6-sulfonyl chloride serves as a versatile derivatization agent, characterized by its sulfonyl chloride functionality that enhances electrophilic reactivity. This compound engages in nucleophilic acyl substitution, enabling the formation of sulfonamide derivatives. Its unique coumarin backbone provides fluorescence properties, allowing for easy tracking of reaction progress. Additionally, the compound's ability to form stable adducts with amines and alcohols streamlines the derivatization process, improving selectivity and efficiency in synthetic pathways.

1-(2-Naphthoyl)imidazole

141903-34-6sc-208528
500 mg
$99.00
(0)

1-(2-Naphthoyl)imidazole is a potent derivatization agent known for its unique naphthoyl moiety, which enhances its reactivity through π-π stacking interactions. This compound facilitates acylation reactions, promoting the formation of imidazole derivatives via nucleophilic attack. Its distinct structure allows for selective targeting of functional groups, improving reaction kinetics and yielding high-purity products. The compound's stability under various conditions further supports its utility in complex synthetic pathways.