Molecular structure of (S)-NIFE, CAS Number: 328406-65-1
(S)-NIFE (CAS 328406-65-1)
See product citations (8)
Alternate Names:
N-(4-Nitrophenoxycarbonyl)-L-phenylalanine 2-methoxyethyl ester
Application:
(S)-NIFE is a novel chiral amino acid derivatizing agent for HPLC
CAS Number:
328406-65-1
Molecular Weight:
388.37
Molecular Formula:
C19H20N2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(S)-NIFE is a novel chiral derivatizing agent for amino acid analysis by HPLC. It is also used for derivatization of secondary amino acids. The mechanism of action of (S)-Nife is based on its ability to bind to amino acids and peptides. When bound, it can alter the structure of the molecule, allowing for the synthesis of proteins with specific properties. It has been used in a variety of scientific research applications, including protein synthesis, drug delivery, and genetic engineering.
(S)-NIFE (CAS 328406-65-1) References
- Application of a new chiral derivatizing agent to the enantioseparation of secondary amino acids. | Péter, A., et al. 2002. J Chromatogr A. 948: 283-94. PMID: 12831204
- A sensitive and simple ultra-high-performance-liquid chromatography-tandem mass spectrometry based method for the quantification of D-amino acids in body fluids. | Visser, WF., et al. 2011. J Chromatogr A. 1218: 7130-6. PMID: 21890145
- Simultaneous analysis of D-alanine, D-aspartic acid, and D-serine using chiral high-performance liquid chromatography-tandem mass spectrometry and its application to the rat plasma and tissues. | Karakawa, S., et al. 2015. J Pharm Biomed Anal. 115: 123-9. PMID: 26186615
- Method development for the determination of D- and L-isomers of leucine in human plasma by high-performance liquid chromatography tandem mass spectrometry and its application to animal plasma samples. | Sugimoto, H., et al. 2015. Anal Bioanal Chem. 407: 7889-98. PMID: 26345443
- Determination of D-serine in human serum by LC-MS/MS using a triazole-bonded column after pre-column derivatization with (S)-4-(3-isothiocyanatopyrrolidin-1-yl)-7- (N, N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole. | Sakamoto, T., et al. 2016. Anal Bioanal Chem. 408: 517-26. PMID: 26542833
- LC-MS/MS method development and validation for quantitative analyses of 2-aminothiazoline-4-carboxylic acid--a new cyanide exposure marker in post mortem blood. | Giebułtowicz, J., et al. 2016. Talanta. 150: 586-92. PMID: 26838446
- CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls. | Biemans, EA., et al. 2016. Neurobiol Aging. 42: 213-6. PMID: 27143438
- Chiral separations for d-amino acid analysis in biological samples. | Szökő, É., et al. 2016. J Pharm Biomed Anal. 130: 100-109. PMID: 27435607
- Development of an online two-dimensional high-performance liquid chromatographic system in combination with tandem mass spectrometric detection for enantiomeric analysis of free amino acids in human physiological fluid. | Ishii, C., et al. 2018. J Chromatogr A. 1570: 91-98. PMID: 30104059
- Preclinical tissue distribution and metabolic correlations of vigabatrin, an antiepileptic drug associated with potential use-limiting visual field defects. | Walters, DC., et al. 2019. Pharmacol Res Perspect. 7: e00456. PMID: 30631446
- Biaryl axially chiral derivatizing agent for simultaneous separation and sensitive detection of proteinogenic amino acid enantiomers using liquid chromatography-tandem mass spectrometry. | Harada, M., et al. 2019. J Chromatogr A. 1593: 91-101. PMID: 30739759
- Three-Dimensional High-Performance Liquid Chromatographic Determination of Asn, Ser, Ala, and Pro Enantiomers in the Plasma of Patients with Chronic Kidney Disease. | Furusho, A., et al. 2019. Anal Chem. 91: 11569-11575. PMID: 31436409
- Sensitive Bromine-Labeled Probe D-BPBr for Simultaneous Identification and Quantification of Chiral Amino Acids and Amino-Containing Metabolites Profiling in Human Biofluid by HPLC/MS. | Shen, K., et al. 2020. Anal Chem. 92: 1763-1769. PMID: 31867963
- Indirect Enantioseparations: Recent Advances in Chiral Metabolomics for Biomedical Research. | Bogos, LG., et al. 2022. Int J Mol Sci. 23: PMID: 35806433
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(S)-NIFE, 25 mg | sc-253524 | 25 mg | $270.00 | |||
(S)-NIFE, 250 mg | sc-253524A | 250 mg | $1224.00 | |||
(S)-NIFE, 500 mg | sc-253524B | 500 mg | $2040.00 | |||
(S)-NIFE, 1 g | sc-253524C | 1 g | $3570.00 | |||
(S)-NIFE, 5 g | sc-253524D | 5 g | $11730.00 |