The category of Dendritic Cell Marker Activators refers to compounds or molecules that have the ability to influence or modulate the expression and function of specific markers or surface antigens on dendritic cells. Dendritic cells are a vital component of the immune system, playing a crucial role in antigen presentation and the initiation of immune responses. These cells are characterized by the presence of specific markers or surface proteins that distinguish them from other immune cells. Dendritic Cell Marker Activators are substances that can impact the expression, activation, or functionality of these markers on dendritic cells, thereby influencing their role in immune responses and antigen presentation.
These activators can have diverse effects on dendritic cell markers, such as upregulating or downregulating their expression, altering their binding affinity to ligands, or modulating their signaling pathways. Researchers use Dendritic Cell Marker Activators to study and manipulate dendritic cell behavior in various contexts, including immune system research, vaccine development, and immunotherapy. Understanding how these activators affect dendritic cell markers is crucial for unraveling the complexities of immune responses, including antigen recognition, immune tolerance, and the development of immune-based interventions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GM-CSF | 83869-56-1 | sc-280759 | 5 µg | $516.00 | 1 | |
GM-CSF is often used in vitro to differentiate and mature dendritic cells from progenitors, upregulating DC markers. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $98.00 $171.00 $425.00 $1560.00 | 12 | |
LPS acts as a potent stimulator of dendritic cell maturation, enhancing the expression of various DC markers. | ||||||
Polyinosinic-polycytidylic acid potassium salt | 31852-29-6 | sc-202767 | 5 mg | $198.00 | ||
Poly I:C mimics viral infection, leading to dendritic cell activation and upregulation of DC markers. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 has been shown to influence dendritic cell phenotype and may modulate the expression of certain markers. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can affect the differentiation and maturation of dendritic cells, influencing marker expression. | ||||||
Zymosan | 9010-72-4 | sc-296863 sc-296863A | 100 mg 1 g | $99.00 $599.00 | 1 | |
Zymosan can stimulate dendritic cell maturation, affecting the expression of specific DC surface markers. | ||||||
R-848 | 144875-48-9 | sc-203231 sc-203231A sc-203231B sc-203231C | 5 mg 25 mg 100 mg 500 mg | $102.00 $306.00 $510.00 $1559.00 | 12 | |
Resiquimod activates dendritic cells via Toll-like receptor signaling, leading to upregulation of DC markers. | ||||||