Deacetylase and Histone Modification
Items 131 to 136 of 136 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH | 125678-68-4 | sc-222009 | 1 mg | $48.00 | ||
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH functions as a potent deacetylase inhibitor, characterized by its unique peptide sequence that enhances binding affinity to histone deacetylases. This compound's specific amino acid composition allows for targeted interactions, stabilizing enzyme-substrate complexes and influencing catalytic efficiency. By altering the deacetylation process, it plays a crucial role in modulating chromatin accessibility and gene expression, highlighting its significance in epigenetic mechanisms. | ||||||
APHS | 209125-28-0 | sc-200668 sc-200668B | 10 mg 100 mg | $330.00 $2045.00 | ||
APHS serves as a selective deacetylase inhibitor, distinguished by its ability to disrupt histone interactions through specific binding motifs. Its structural conformation facilitates unique hydrogen bonding and hydrophobic interactions with target enzymes, enhancing its inhibitory potency. By modulating the acetylation state of histones, APHS influences chromatin remodeling and transcriptional regulation, thereby impacting cellular signaling pathways and gene regulatory networks. | ||||||
Fmoc-L-Lys(Me2)-OH*HCl | 252049-10-8 | sc-294919 | 250 mg | $300.00 | ||
Fmoc-L-Lys(Me2)-OH*HCl acts as a potent deacetylase inhibitor, characterized by its unique side chain modifications that enhance binding affinity to histone deacetylases. The presence of the Fmoc group allows for specific π-π stacking interactions, while the dimethylated lysine residue introduces steric hindrance, altering enzyme kinetics. This compound's ability to stabilize enzyme-substrate complexes can significantly influence histone acetylation dynamics, thereby affecting chromatin structure and gene expression. | ||||||
HNHA | 926908-04-5 | sc-205343 sc-205343A | 5 mg 10 mg | $161.00 $405.00 | ||
HNHA functions as a selective deacetylase inhibitor, distinguished by its unique structural features that facilitate strong interactions with histone deacetylases. Its specific functional groups promote hydrogen bonding and hydrophobic interactions, enhancing binding specificity. The compound's kinetic profile reveals a competitive inhibition mechanism, which modulates the activity of deacetylases, ultimately impacting histone modification patterns and chromatin remodeling processes. | ||||||
SB939 | 929016-96-6 | sc-364610 sc-364610A | 5 mg 50 mg | $205.00 $834.00 | ||
SB939 is a potent deacetylase inhibitor characterized by its ability to disrupt the interaction between histones and deacetylases through unique molecular conformations. Its distinct binding affinity is attributed to specific electrostatic interactions and steric hindrance, which alter the enzyme's active site dynamics. This compound exhibits a non-linear reaction kinetics profile, influencing the rate of histone acetylation and subsequent chromatin accessibility, thereby affecting gene expression regulation. | ||||||
Coumarin-SAHA | 1260635-77-5 | sc-391815 sc-391815A | 1 mg 10 mg | $56.00 $216.00 | ||
Coumarin-SAHA functions as a deacetylase inhibitor by engaging in selective binding with histone deacetylases, leading to conformational changes that hinder their enzymatic activity. Its unique structural features facilitate strong hydrogen bonding and hydrophobic interactions, enhancing its specificity. The compound's kinetic behavior reveals a complex modulation of histone acetylation rates, impacting chromatin structure and influencing transcriptional regulation through altered protein interactions. | ||||||