Deacetylase and Histone Modification
Items 121 to 130 of 136 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
7-Aminoindole | 5192-04-1 | sc-257005 | 1 g | $555.00 | ||
7-Aminoindole functions as a potent deacetylase inhibitor, engaging in specific interactions with histone proteins to modulate chromatin structure. Its unique ability to disrupt the deacetylation process leads to altered gene expression profiles. The compound exhibits distinct reaction kinetics, influencing the stability of histone modifications. By selectively targeting deacetylases, it plays a crucial role in regulating epigenetic landscapes and cellular signaling pathways. | ||||||
Aristoforin | 849215-53-8 | sc-202958 | 1 mg | $151.00 | 1 | |
Aristoforin acts as a selective deacetylase inhibitor, intricately interacting with histone proteins to influence chromatin dynamics. Its unique binding affinity alters the enzymatic activity of deacetylases, resulting in significant changes to histone acetylation states. This compound exhibits distinctive reaction kinetics, enhancing the persistence of acetylated histones, thereby impacting transcriptional regulation and chromatin accessibility. Its role in modulating epigenetic mechanisms is pivotal for cellular function. | ||||||
cGKI inhibitor | sc-3042 | 0.5 mg/0.1 ml | $95.00 | |||
cGKI inhibitor functions as a potent deacetylase inhibitor, engaging in specific molecular interactions that disrupt the deacetylation of histones. By stabilizing acetylated lysine residues, it alters the conformational landscape of chromatin, influencing gene expression patterns. The compound exhibits unique reaction kinetics, promoting a prolonged presence of acetylated histones, which can lead to enhanced chromatin relaxation and accessibility, thereby affecting epigenetic regulation. | ||||||
HDAC Inhibitor XXIV | sc-364505 | 10 mg | $225.00 | |||
HDAC Inhibitor XXIV acts as a selective deacetylase inhibitor, targeting histone proteins to modulate their acetylation status. Its unique binding affinity facilitates the formation of stable enzyme-inhibitor complexes, effectively hindering the deacetylation process. This compound exhibits distinctive kinetic properties, allowing for a gradual accumulation of acetylated histones, which can significantly impact chromatin structure and dynamics, thereby influencing cellular processes at the epigenetic level. | ||||||
Ac-Arg-Gly-Lys-MCA | sc-391017 sc-391017A | 1 mg 5 mg | $45.00 $180.00 | |||
Ac-Arg-Gly-Lys-MCA functions as a potent deacetylase inhibitor, specifically interacting with histone proteins to alter their acetylation. Its unique structure promotes strong interactions with the active site of deacetylases, leading to a significant reduction in enzymatic activity. The compound's kinetic profile reveals a slow dissociation rate, allowing for sustained inhibition and prolonged effects on histone modification, ultimately affecting chromatin accessibility and gene expression regulation. | ||||||
2,2,2-Trichloroethyl acetate | 625-24-1 | sc-256253 | 5 ml | $226.00 | ||
2,2,2-Trichloroethyl acetate acts as a selective deacetylase inhibitor, engaging with histone proteins through specific hydrogen bonding and hydrophobic interactions. Its unique trifluoromethyl group enhances lipophilicity, facilitating membrane permeability and targeted action. The compound exhibits a distinctive reaction kinetics profile, characterized by a gradual onset of inhibition, which allows for a nuanced modulation of histone acetylation dynamics, influencing chromatin structure and function. | ||||||
Butyrylhydroxamic acid | 4312-91-8 | sc-364450 sc-364450A | 5 mg 25 mg | $65.00 $278.00 | ||
Butyrylhydroxamic acid functions as a potent deacetylase inhibitor, interacting with histone proteins via a unique chelation mechanism that stabilizes the enzyme-substrate complex. Its hydroxamic acid moiety forms strong hydrogen bonds, enhancing specificity and affinity. The compound's distinct steric properties influence its binding kinetics, allowing for a controlled modulation of histone deacetylation, thereby impacting gene expression and chromatin remodeling processes. | ||||||
4-(3,4-Dimethoxyphenyl)butyric acid | 13575-74-1 | sc-226371 | 5 g | $54.00 | ||
4-(3,4-Dimethoxyphenyl)butyric acid acts as a selective deacetylase inhibitor, engaging in specific interactions with histone proteins through its unique aromatic structure. The methoxy groups enhance electron density, facilitating π-π stacking with histone residues. This compound exhibits a distinctive binding profile, promoting conformational changes in the enzyme that modulate catalytic activity. Its structural features contribute to a nuanced regulation of histone acetylation, influencing chromatin dynamics. | ||||||
Demethoxy Curcumin | 22608-11-3 | sc-391590 | 10 mg | $268.00 | ||
Demethoxy Curcumin functions as a potent deacetylase inhibitor, characterized by its ability to interact with histone proteins via its unique polyphenolic structure. The compound's hydroxyl groups enable hydrogen bonding and hydrophobic interactions, stabilizing its binding to the enzyme's active site. This interaction leads to altered enzyme kinetics, enhancing histone acetylation levels and subsequently affecting gene expression regulation. Its distinct molecular architecture plays a crucial role in modulating chromatin accessibility. | ||||||
Triacetylresveratrol | 42206-94-0 | sc-358583 sc-358583A | 1 g 5 g | $216.00 $772.00 | ||
Triacetylresveratrol acts as a selective deacetylase inhibitor, showcasing a unique ability to modulate histone dynamics through its acetylated phenolic framework. The compound's structural features facilitate specific interactions with deacetylase enzymes, promoting conformational changes that influence substrate affinity. This modulation of enzyme activity alters the acetylation status of histones, thereby impacting chromatin structure and gene transcription processes. Its intricate molecular design underscores its role in epigenetic regulation. | ||||||