Date published: 2026-4-25

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DDEFL1 Inhibitors

DDEFL1 inhibitors are a category of chemical compounds designed to target and modulate the activity of the DDEFL1 protein, also known as Development and Differentiation Enhancing Factor-Like 1. DDEFL1 is a relatively newly discovered protein that is being actively researched for its potential roles in cellular processes, particularly in the context of development and differentiation. Inhibitors of DDEFL1 are developed to interact with this specific protein, potentially influencing its functions in cellular development and differentiation, as the name suggests.

Structurally, DDEFL1 inhibitors are designed to engage specific regions or binding sites on the DDEFL1 protein. This interaction can disrupt the normal functioning of DDEFL1, potentially affecting its roles in cellular processes such as embryonic development, tissue differentiation, and cell fate determination. The precise mechanisms by which DDEFL1 inhibitors exert their effects are still under investigation, but they represent valuable tools for researchers exploring the intricate molecular mechanisms governing cellular development. As our understanding of DDEFL1 and its modulation by inhibitors advances, it may provide insights into the complex processes that drive cellular differentiation and tissue formation, with potential implications in various areas of biology and medicine.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$186.00
$707.00
88
(1)

A Rho-associated protein kinase (ROCK) inhibitor. Given DDEFL1's role in actin organization, inhibiting ROCK can indirectly affect its function.

(±)-Blebbistatin

674289-55-5sc-203532B
sc-203532
sc-203532A
sc-203532C
sc-203532D
5 mg
10 mg
25 mg
50 mg
100 mg
$183.00
$313.00
$464.00
$942.00
$1723.00
7
(1)

A myosin II inhibitor that can influence actin dynamics and potentially alter DDEFL1-mediated processes.

Latrunculin A, Latrunculia magnifica

76343-93-6sc-202691
sc-202691B
100 µg
500 µg
$265.00
$815.00
36
(2)

This compound binds to actin monomers and inhibits polymerization. Might impact DDEFL1's function in actin organization.

Cytochalasin D

22144-77-0sc-201442
sc-201442A
1 mg
5 mg
$165.00
$486.00
64
(4)

It inhibits actin polymerization, which can have implications for DDEFL1's role in actin dynamics.

EHT 1864

754240-09-0sc-361175
sc-361175A
10 mg
50 mg
$213.00
$889.00
12
(2)

A Rac family small GTPase inhibitor, which might impact pathways related to DDEFL1.

ML 141

71203-35-5sc-362768
sc-362768A
5 mg
25 mg
$137.00
$512.00
7
(1)

An inhibitor of Cdc42, another potential interactor of DDEFL1.

CK 666

442633-00-3sc-361151
sc-361151A
10 mg
50 mg
$321.00
$1040.00
5
(0)

An Arp2/3 complex inhibitor. Given DDEFL1's role in actin dynamics, this might indirectly influence its function.

IPA 3

42521-82-4sc-204016
sc-204016A
5 mg
50 mg
$94.00
$458.00
6
(1)

A PAK1 inhibitor that might interfere with pathways related to DDEFL1's function in actin dynamics.

PF-3758309

898044-15-0sc-478493
10 mg
$260.00
(0)

Inhibits PAK4, potentially influencing DDEFL1-mediated cellular processes.

H-1152 dihydrochloride

451462-58-1sc-203592
sc-203592A
1 mg
5 mg
$104.00
$364.00
7
(1)

A ROCK inhibitor that might impact the actin cytoskeleton and indirectly influence DDEFL1's role.