DDB1 Activators
DDB1 Activators represent a diverse class of compounds designed to enhance the functional activity of DDB1 (DNA damage-binding protein 1). These activators act through various mechanisms, directly or indirectly influencing cellular processes and molecular interactions in which DDB1 plays a crucial role. Compounds such as GSK-J1, UNC1999, JIB-04, GSK343, CPI-1205, and GSK126 directly enhance the functional activity of DDB1 by modulating histone methylation through the inhibition of JMJD3, UTX, or EZH2. This direct enhancement promotes the activation of DDB1 and its involvement in cellular processes and molecular interactions.
Additionally, compounds like UNC0638, EPZ-6438, JIB-25, GSK-2879552, GSK-1260882, and CPI-169 indirectly enhance DDB1 activity by influencing histone methylation pathways. These chemicals indirectly activate DDB1 by modulating histone methylation processes, specifically H3K27me3, associated with JMJD3, UTX, or EZH2. This indirect enhancement contributes to the activation of DDB1 and its participation in various cellular processes and molecular interactions. The versatility of DDB1 Activators provides researchers with valuable tools to modulate the intricate functions of DDB1, contributing to a deeper understanding of its role in cellular processes and molecular pathways.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
GSK J1 | 1373422-53-7 | sc-391113 sc-391113A | 10 mg 50 mg | $189.00 $797.00 | ||
GSK-J1 is a chemical compound known to directly enhance the functional activity of DDB1. It achieves this by inhibiting the Jumonji domain-containing demethylases, specifically JMJD3 and UTX. | ||||||
UNC1999 | 1431612-23-5 | sc-475314 | 5 mg | $142.00 | 1 | |
UNC1999 is a chemical compound that directly enhances the functional activity of DDB1. It achieves this by inhibiting the activity of the lysine methyltransferase enzyme EZH2. The enhanced activity of DDB1 is linked to the modulation of histone methylation, specifically the methylation of H3K27 by EZH2. | ||||||
JIB 04 | 199596-05-9 | sc-397040 | 20 mg | $177.00 | ||
JIB-04 is a chemical compound known to directly enhance the functional activity of DDB1. It achieves this by inhibiting the Jumonji domain-containing demethylases, including JMJD3 and UTX. | ||||||
GSK343 | 1346704-33-3 | sc-397025 sc-397025A | 5 mg 25 mg | $148.00 $452.00 | 1 | |
GSK343 is a chemical compound that directly enhances the functional activity of DDB1. It achieves this by inhibiting the activity of the lysine methyltransferase enzyme EZH2. The enhanced activity of DDB1 is linked to the modulation of histone methylation, specifically the methylation of H3K27 by EZH2. | ||||||
GSK126 | 1346574-57-9 | sc-490133 sc-490133A sc-490133B | 1 mg 5 mg 10 mg | $90.00 $238.00 $300.00 | ||
GSK126 is a chemical compound that directly enhances the functional activity of DDB1. It achieves this by inhibiting the activity of the lysine methyltransferase enzyme EZH2. The enhanced activity of DDB1 is linked to the modulation of histone methylation, specifically the methylation of H3K27 by EZH2. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
UNC0638 is a chemical compound known to directly enhance the functional activity of DDB1. It achieves this by inhibiting the Jumonji domain-containing demethylases, including JMJD3 and UTX. The enhanced activity of DDB1 is linked to the modulation of histone methylation, particularly H3K27me3, which is catalyzed by JMJD3 and UTX. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
EPZ-6438 is a chemical compound that directly enhances the functional activity of DDB1. It achieves this by inhibiting the activity of the lysine methyltransferase enzyme EZH2. The enhanced activity of DDB1 is linked to the modulation of histone methylation, specifically the methylation of H3K27 by EZH2. | ||||||