Date published: 2026-2-14

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DBX1 Inhibitors

DBX1 inhibitors constitute a distinctive class of chemical entities engineered to modulate the activity of the DBX1 gene, a pivotal regulator in the realm of embryonic development and cellular differentiation processes. DBX1, also recognized as Developing Brain Homeobox 1, stands as a transcription factor with an indispensable role in orchestrating the patterning and specification of neural tissues during the early stages of embryogenesis. It is crucial to emphasize that DBX1 inhibitors are primarily developed for research purposes, with their fundamental objective being the unraveling of intricate mechanisms underlying neural development, as they are not intended for applications.

These inhibitors manifest themselves in various forms, such as small molecules, peptides, or chemical compounds, and their principal mechanism of action lies in disrupting specific protein-protein interactions or DNA binding sites that are critical for DBX1's functional role. Researchers wield these inhibitors as potent tools to dissect the precise functions of DBX1 in neural differentiation and to explore its intricate interactions with other developmental genes. By hindering the transcriptional regulation of DBX1, these inhibitors obstruct its capacity to activate or suppress downstream target genes, offering invaluable insights into the regulatory networks and signaling pathways entailed in neural development. Consequently, DBX1 inhibitors serve as indispensable instruments in enhancing our comprehension of embryonic development, shedding light on the complex molecular processes that underlie the formation of the central nervous system.It is paramount to underscore that DBX1 inhibitors primarily function as research reagents, dedicated to the elucidation of DBX1-mediated neural patterning and differentiation, rather than serving as agents.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Indomethacin

53-86-1sc-200503
sc-200503A
1 g
5 g
$29.00
$38.00
18
(1)

Indomethacin is a non-selective COX inhibitor that blocks the production of prostaglandins, which play a role in DBX1 signaling pathways.

Sulindac

38194-50-2sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$32.00
$86.00
$150.00
3
(1)

Sulindac inhibits COX enzymes, lowering prostaglandin levels, which could impact DBX1-related processes.

Naproxen

22204-53-1sc-200506
sc-200506A
1 g
5 g
$24.00
$41.00
(1)

Naproxen is a non-selective COX inhibitor that reduces prostaglandin synthesis, affecting DBX1 signaling pathways.

Meloxicam

71125-38-7sc-200626
sc-200626A
sc-200626B
20 mg
100 mg
500 mg
$36.00
$94.00
$156.00
3
(1)

Meloxicam selectively inhibits COX-2, potentially interfering with DBX1-related processes mediated by prostaglandins.

Diclofenac Sodium

15307-79-6sc-202136
sc-202136A
5 g
25 g
$41.00
$128.00
4
(1)

Diclofenac is a non-selective COX inhibitor that reduces prostaglandin production, which could impact DBX1 signaling pathways.

Piroxicam

36322-90-4sc-200576
sc-200576A
1 g
5 g
$109.00
$376.00
2
(0)

Piroxicam inhibits COX enzymes, lowering prostaglandin levels and potentially interfering with DBX1 pathway activation.

Vioxx

162011-90-7sc-208486
100 mg
$190.00
3
(1)

Rofecoxib selectively inhibits COX-2, potentially interfering with DBX1-related processes mediated by prostaglandins.

Etodolac

41340-25-4sc-204747
sc-204747A
100 mg
250 mg
$89.00
$131.00
1
(1)

Etodolac inhibits COX enzymes, lowering prostaglandin levels, which could impact DBX1 signaling pathways.

Nabumetone

42924-53-8sc-204813
sc-204813A
5 g
25 g
$200.00
$599.00
3
(1)

Nabumetone is a prodrug that inhibits COX enzymes, reducing prostaglandin production and potentially interfering with DBX1 pathway activation.