DBX1 inhibitors constitute a distinctive class of chemical entities engineered to modulate the activity of the DBX1 gene, a pivotal regulator in the realm of embryonic development and cellular differentiation processes. DBX1, also recognized as Developing Brain Homeobox 1, stands as a transcription factor with an indispensable role in orchestrating the patterning and specification of neural tissues during the early stages of embryogenesis. It is crucial to emphasize that DBX1 inhibitors are primarily developed for research purposes, with their fundamental objective being the unraveling of intricate mechanisms underlying neural development, as they are not intended for applications.
These inhibitors manifest themselves in various forms, such as small molecules, peptides, or chemical compounds, and their principal mechanism of action lies in disrupting specific protein-protein interactions or DNA binding sites that are critical for DBX1's functional role. Researchers wield these inhibitors as potent tools to dissect the precise functions of DBX1 in neural differentiation and to explore its intricate interactions with other developmental genes. By hindering the transcriptional regulation of DBX1, these inhibitors obstruct its capacity to activate or suppress downstream target genes, offering invaluable insights into the regulatory networks and signaling pathways entailed in neural development. Consequently, DBX1 inhibitors serve as indispensable instruments in enhancing our comprehension of embryonic development, shedding light on the complex molecular processes that underlie the formation of the central nervous system.It is paramount to underscore that DBX1 inhibitors primarily function as research reagents, dedicated to the elucidation of DBX1-mediated neural patterning and differentiation, rather than serving as agents.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Indomethacin | 53-86-1 | sc-200503 sc-200503A | 1 g 5 g | $29.00 $38.00 | 18 | |
Indomethacin is a non-selective COX inhibitor that blocks the production of prostaglandins, which play a role in DBX1 signaling pathways. | ||||||
Sulindac | 38194-50-2 | sc-202823 sc-202823A sc-202823B | 1 g 5 g 10 g | $32.00 $86.00 $150.00 | 3 | |
Sulindac inhibits COX enzymes, lowering prostaglandin levels, which could impact DBX1-related processes. | ||||||
Naproxen | 22204-53-1 | sc-200506 sc-200506A | 1 g 5 g | $24.00 $41.00 | ||
Naproxen is a non-selective COX inhibitor that reduces prostaglandin synthesis, affecting DBX1 signaling pathways. | ||||||
Meloxicam | 71125-38-7 | sc-200626 sc-200626A sc-200626B | 20 mg 100 mg 500 mg | $36.00 $94.00 $156.00 | 3 | |
Meloxicam selectively inhibits COX-2, potentially interfering with DBX1-related processes mediated by prostaglandins. | ||||||
Diclofenac Sodium | 15307-79-6 | sc-202136 sc-202136A | 5 g 25 g | $41.00 $128.00 | 4 | |
Diclofenac is a non-selective COX inhibitor that reduces prostaglandin production, which could impact DBX1 signaling pathways. | ||||||
Piroxicam | 36322-90-4 | sc-200576 sc-200576A | 1 g 5 g | $109.00 $376.00 | 2 | |
Piroxicam inhibits COX enzymes, lowering prostaglandin levels and potentially interfering with DBX1 pathway activation. | ||||||
Vioxx | 162011-90-7 | sc-208486 | 100 mg | $190.00 | 3 | |
Rofecoxib selectively inhibits COX-2, potentially interfering with DBX1-related processes mediated by prostaglandins. | ||||||
Etodolac | 41340-25-4 | sc-204747 sc-204747A | 100 mg 250 mg | $89.00 $131.00 | 1 | |
Etodolac inhibits COX enzymes, lowering prostaglandin levels, which could impact DBX1 signaling pathways. | ||||||
Nabumetone | 42924-53-8 | sc-204813 sc-204813A | 5 g 25 g | $200.00 $599.00 | 3 | |
Nabumetone is a prodrug that inhibits COX enzymes, reducing prostaglandin production and potentially interfering with DBX1 pathway activation. | ||||||