CYP2B6 Substrates
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(S)-Mephenytoin | 70989-04-7 | sc-200975 sc-200975A | 5 mg 25 mg | $142.00 $550.00 | 14 | |
(S)-Mephenytoin exhibits notable interactions with CYP2B6, characterized by its chiral center that influences binding dynamics. The presence of the ethyl group enhances hydrophobic interactions, promoting a stable enzyme-substrate complex. Additionally, the compound's stereochemistry plays a crucial role in modulating the enzyme's active site, leading to distinct metabolic pathways. Its unique electronic properties contribute to varied reaction kinetics, impacting overall enzymatic activity and selectivity. | ||||||
Resorufin pentyl ether | 87687-03-4 | sc-208304 sc-208304A | 1 mg 5 mg | $204.00 $632.00 | 2 | |
Resorufin pentyl ether demonstrates intriguing interactions with CYP2B6, primarily due to its hydrophobic pentyl chain, which enhances affinity for the enzyme's active site. This compound's unique electronic structure facilitates electron transfer processes, influencing the rate of metabolic reactions. The ether functionality allows for specific hydrogen bonding, further stabilizing enzyme-substrate complexes. Its distinct steric properties can modulate substrate accessibility, affecting overall catalytic efficiency and selectivity in metabolic pathways. | ||||||
7-Ethoxycoumarin | 31005-02-4 | sc-207170 sc-207170A | 25 mg 100 mg | $41.00 $71.00 | ||
7-Ethoxycoumarin exhibits notable characteristics when interacting with CYP2B6, primarily through its ethoxy group, which enhances solubility and promotes favorable binding interactions. The compound's planar structure allows for effective π-π stacking with aromatic residues in the enzyme, influencing binding affinity. Additionally, its unique electron-donating properties can alter the redox state of the enzyme, impacting reaction kinetics and metabolic stability. The compound's conformational flexibility may also play a role in modulating enzyme activity and substrate turnover. | ||||||
(R)-Mephenytoin | 71140-51-7 | sc-215780 | 10 mg | $260.00 | ||
(R)-Mephenytoin demonstrates intriguing interactions with CYP2B6, primarily due to its chiral center, which influences stereoselectivity in metabolic pathways. The compound's hydrophobic regions facilitate strong van der Waals interactions with the enzyme's active site, enhancing binding efficiency. Its unique electronic configuration can modulate the enzyme's catalytic activity, while the presence of specific functional groups may affect substrate recognition and turnover rates, leading to distinct metabolic profiles. | ||||||