Molecular structure of (R)-Mephenytoin, CAS Number: 71140-51-7
(R)-Mephenytoin (CAS 71140-51-7)
Application:
(R)-Mephenytoin is an anticonvulsant agent
CAS Number:
71140-51-7
Molecular Weight:
218.25
Molecular Formula:
C12H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(R)-Mephenytoin is an anticonvulsant agent.
(R)-Mephenytoin (CAS 71140-51-7) References
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- Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9. | Simonsson, US., et al. 2003. Clin Pharmacol Ther. 74: 32-43. PMID: 12844133
- Sparteine and mephenytoin oxidation: genetic polymorphisms in east and west Greenland. | Clasen, K., et al. 1991. Clin Pharmacol Ther. 49: 624-31. PMID: 2060251
- Mephenytoin stereoselective elimination in the rat: I. Enantiomeric disposition following intravenous administration. | Akrawi, SH. and Wedlund, PJ. 1989. Eur J Drug Metab Pharmacokinet. 14: 195-200. PMID: 2612516
- Mephenytoin stereoselective elimination in the rat: II. Comparison of mephenytoin stereoselective clearance during chronic intravenous and hepatic portal vein administration. | Akrawi, SH. and Wedlund, PJ. 1989. Eur J Drug Metab Pharmacokinet. 14: 269-78. PMID: 2633921
- Polymorphic metabolism of mephenytoin in man: pharmacokinetic interaction with a co-regulated substrate, mephobarbital. | Jacqz, E., et al. 1986. Clin Pharmacol Ther. 39: 646-53. PMID: 3709029
- The genetic defect of mephenytoin hydroxylation. | Kalow, W. 1986. Xenobiotica. 16: 379-89. PMID: 3739364
- Phenotypic differences in mephenytoin pharmacokinetics in normal subjects. | Wedlund, PJ., et al. 1985. J Pharmacol Exp Ther. 234: 662-9. PMID: 4032286
- Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo. | Meier, UT., et al. 1985. Clin Pharmacol Ther. 38: 488-94. PMID: 4053486
- Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography. | Meier, UT., et al. 1985. Anal Biochem. 151: 286-91. PMID: 4096368
- Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography. | Wedlund, PJ., et al. 1984. J Chromatogr. 307: 121-7. PMID: 6725478
- The hydroxylation of omeprazole correlates with S-mephenytoin and proguanil metabolism. | Kortunay, S., et al. 1997. Eur J Clin Pharmacol. 53: 261-4. PMID: 9476042
- Selective effect of liver disease on the activities of specific metabolizing enzymes: investigation of cytochromes P450 2C19 and 2D6. | Adedoyin, A., et al. 1998. Clin Pharmacol Ther. 64: 8-17. PMID: 9695714
Substrate of:
CYP2B6, and CYP2C19.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(R)-Mephenytoin, 10 mg | sc-215780 | 10 mg | $260.00 |