cyclin O Inhibitors
Cyclin O inhibitors are chemicals that target and inhibit the function of cyclin O, a protein that plays a role in various cellular processes. Cyclin O, although not as widely studied as other cyclins, has been identified as having a role in cell cycle regulation and other cellular mechanisms. Cyclin O inhibitors can bind to cyclin O, potentially disrupting its interaction with other cell cycle proteins and thus influencing its role in cellular regulation. These inhibitors may have a combination of functional groups and structural motifs that are strategically aligned to interact with specific domains of cyclin O. This may include hydrophobic chains, aromatic rings, and hydrogen bond donors or acceptors, all arranged in a manner that enhances the specificity and efficacy of binding to cyclin O.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A cytidine analog that incorporates into RNA and DNA and can disrupt DNA methylation, potentially reducing CCNO transcription. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Interacts with DNA and inhibits RNA polymerase action, which could nonspecifically inhibit CCNO mRNA synthesis. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits eukaryotic protein synthesis, potentially reducing CCNO protein levels by preventing translation. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Binds to DNA and inhibits RNA synthesis, which may decrease the transcription of CCNO. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Can alter DNA and RNA synthesis, which might nonspecifically reduce CCNO expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I, which could indirectly affect CCNO transcription by altering DNA transcription dynamics. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Specifically inhibits RNA polymerase II, which could lead to reduced transcription of CCNO mRNA. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $42.00 $185.00 $310.00 $650.00 | 6 | |
Inhibits RNA synthesis by blocking RNA polymerase II, potentially decreasing CCNO expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Inhibits cyclin-dependent kinases that regulate transcription and could decrease CCNO mRNA levels. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Known to inhibit transcription broadly, which could result in decreased CCNO mRNA levels. | ||||||