cyclin B1 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
RO-3306 | 872573-93-8 | sc-358700 sc-358700A sc-358700B | 1 mg 5 mg 25 mg | $65.00 $160.00 $320.00 | 37 | |
RO-3306 functions as a selective inhibitor of cyclin-dependent kinases, particularly targeting CDK1. Its unique binding affinity enables it to disrupt the cyclin B1-CDK1 complex, leading to altered phosphorylation states of key substrates. The compound's specific steric configuration enhances its interaction with the ATP-binding site, modulating kinase activity with high specificity. This selective inhibition can significantly impact cell cycle progression and checkpoint regulation. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol is a synthetic flavone derivative that inhibits multiple CDKs, including CDK1 and CDKBy targeting cyclin B1/CDK1 complex, flavopiridol prevents cell cycle progression and induces apoptosis in cancer cells. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $71.00 $291.00 | 4 | |
Purvalanol A is a potent and selective inhibitor of CDK1 and CDKIt effectively inhibits cyclin B1/CDK1 activity and induces G2/M cell cycle arrest in various cancer cell lines. | ||||||
SNS-032 | 345627-80-7 | sc-364621 sc-364621A | 5 mg 10 mg | $169.00 $262.00 | ||
SNS-032 is a selective inhibitor of CDK2, CDK7, and CDKBy inhibiting CDK2, it indirectly affects the activity of cyclin B1/CDK1 complex, leading to cell cycle arrest and apoptosis. | ||||||
Polo-like Kinase Inhibitor III | 660868-91-7 | sc-203202 | 500 µg | $107.00 | 1 | |
GW843682X is a selective inhibitor of CDK1 and CDKIt blocks the kinase activity of cyclin B1/CDK1 complex, resulting in G2/M arrest and subsequent cell death. | ||||||
AZD 5438 | 602306-29-6 | sc-361115 sc-361115A | 10 mg 50 mg | $205.00 $865.00 | ||
AZD5438 is a potent and selective inhibitor of CDK1, CDK2, and CDKIt effectively inhibits the activity of cyclin B1/CDK1 complex and induces cell cycle arrest in cancer cells. | ||||||
R547 | 741713-40-6 | sc-364596 sc-364596A | 2 mg 5 mg | $375.00 $395.00 | ||
R547 is a selective inhibitor of CDK1, CDK2, and CDKIt disrupts the cyclin B1/CDK1 complex and inhibits cell cycle progression, leading to growth inhibition of cancer cells. | ||||||
Dinaciclib | 779353-01-4 | sc-364483 sc-364483A | 5 mg 25 mg | $242.00 $871.00 | 1 | |
Dinaciclib is a potent inhibitor of CDK1, CDK2, CDK5, and CDKBy inhibiting CDK1, it directly affects the activity of cyclin B1/CDK1 complex, leading to cell cycle arrest and apoptosis. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
CYC202, also known as Seliciclib, is a pan-CDK inhibitor that targets CDK1, CDK2, CDK7, and CDKIt inhibits the cyclin B1/CDK1 complex and induces G2/M cell cycle arrest in cancer cells. | ||||||
Aurora Kinase/Cdk Inhibitor | 443797-96-4 | sc-203829 | 5 mg | $440.00 | ||
JNJ-7706621 is a selective inhibitor of CDK1 and CDKIt inhibits the activity of cyclin B1/CDK1 complex and induces cell cycle arrest at the G2/M phase. | ||||||