Cup1 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Copper(II) sulfate | 7758-98-7 | sc-211133 sc-211133A sc-211133B | 100 g 500 g 1 kg | $45.00 $120.00 $185.00 | 3 | |
Elevated copper levels, such as those from copper(II) sulfate, can downregulate Cup1 expression through a feedback inhibition mechanism, as the cell attempts to maintain copper homeostasis. | ||||||
Silver nitrate | 7761-88-8 | sc-203378 sc-203378A sc-203378B | 25 g 100 g 500 g | $112.00 $371.00 $1060.00 | 1 | |
Silver ions from silver nitrate may displace copper, leading to a decrease in Cup1 expression due to interference with copper-dependent transcription factors that control the CUP1 gene promoter. | ||||||
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $76.00 $216.00 | 101 | |
By forming DNA adducts, cisplatin can obstruct the transcriptional machinery′s access to the CUP1 promoter, thereby reducing transcription rates and subsequent Cup1 protein synthesis. | ||||||
Sodium arsenite, 0.1N Standardized Solution | 7784-46-5 | sc-301816 | 500 ml | $130.00 | 4 | |
Sodium arsenite could disrupt the binding of transcription factors to metal response elements on the CUP1 gene, resulting in a decreased expression of the Cup1 protein. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $55.00 $179.00 $345.00 | 1 | |
Cadmium chloride may interfere with the normal induction of Cup1 expression by competing with copper ions and other metals that are crucial for the gene′s upregulation. | ||||||
Lead(II) Acetate | 301-04-2 | sc-507473 | 5 g | $83.00 | ||
Lead(II) acetate exposure can cause a downregulation of Cup1 expression as lead competes with copper and other metal ions for binding sites on transcription factor proteins specific to the CUP1 gene. | ||||||
Zinc sulfate solution | 7733-02-0 | sc-251451 | 250 ml | $110.00 | ||
An excess of zinc, provided by zinc sulfate, can downregulate Cup1 expression by disturbing the metal ion balance necessary for the proper transcription of metallothionein genes like CUP1. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $68.00 $210.00 $780.00 $1880.00 | 19 | |
N-Ethylmaleimide reacts with cysteine residues, which could result in reduced expression of Cup1 by altering the function of transcription factors that govern the expression of the CUP1 gene. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $30.00 $60.00 $93.00 | 27 | |
Hydrogen peroxide can induce oxidative stress, which may lead to a downregulation of Cup1 expression as part of a broader cellular response to mitigate damage from reactive oxygen species. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone could decrease Cup1 expression by activating glucocorticoid receptors, which may interact with transcription factors or coactivators involved in the transcriptional control of the CUP1 gene. | ||||||