Date published: 2026-2-14

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CSAGE Inhibitors

CSAGE inhibitors, short for Cell Signaling and Growth Arresting Inhibitors, constitute a diverse class of chemical compounds designed to modulate cellular processes crucial for signal transduction, proliferation, and growth regulation in living organisms. These inhibitors are primarily employed in laboratory research settings and studies to dissect the intricate web of molecular interactions within cells. Their primary function is to interfere with specific intracellular signaling pathways, thereby allowing scientists to elucidate the roles of individual proteins and cascades in cell function and dysfunction.

CSAGE inhibitors encompass a wide range of chemical structures and mechanisms of action, making them versatile tools for cell biology and molecular research. These inhibitors often target key kinases and enzymes involved in signal transduction, including receptor tyrosine kinases, serine/threonine kinases, and downstream effectors. By selectively inhibiting these molecular players, CSAGE inhibitors enable researchers to dissect the intricacies of signaling networks, uncover targets, and gain valuable insights into the molecular underpinnings of various diseases. Moreover, these inhibitors can serve as indispensable tools for studying cellular processes such as cell cycle regulation, apoptosis, and differentiation, shedding light on fundamental aspects of cell biology. Overall, CSAGE inhibitors play a pivotal role in advancing our understanding of cellular signaling pathways and their dysregulation, laying the foundation for future interventions.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Gefitinib

184475-35-2sc-202166
sc-202166A
sc-202166B
sc-202166C
100 mg
250 mg
1 g
5 g
$63.00
$114.00
$218.00
$349.00
74
(2)

Inhibits EGFR tyrosine kinase, blocking signaling pathways that promote cell growth and division in cancer cells.

Imatinib

152459-95-5sc-267106
sc-267106A
sc-267106B
10 mg
100 mg
1 g
$26.00
$119.00
$213.00
27
(1)

Targets BCR-ABL tyrosine kinase, inhibiting its activity in chronic myeloid leukemia (CML) and other malignancies.

Sorafenib

284461-73-0sc-220125
sc-220125A
sc-220125B
5 mg
50 mg
500 mg
$57.00
$100.00
$250.00
129
(3)

Inhibits multiple kinases involved in tumor angiogenesis and cell proliferation, often used for liver and kidney cancers.

Trametinib

871700-17-3sc-364639
sc-364639A
sc-364639B
5 mg
10 mg
1 g
$114.00
$166.00
$947.00
19
(1)

Blocks MEK, a key component of the MAPK pathway, thereby inhibiting cell growth and division in various cancers.

Everolimus

159351-69-6sc-218452
sc-218452A
5 mg
50 mg
$131.00
$651.00
7
(1)

Targets mTOR, a central regulator of cell growth and proliferation, often used in certain cancers.

Erlotinib, Free Base

183321-74-6sc-396113
sc-396113A
sc-396113B
sc-396113C
sc-396113D
500 mg
1 g
5 g
10 g
100 g
$87.00
$135.00
$293.00
$505.00
$3827.00
42
(0)

Inhibits EGFR tyrosine kinase, disrupting signaling cascades responsible for promoting cancer cell survival and growth.

Lapatinib

231277-92-2sc-353658
100 mg
$420.00
32
(1)

Targets both EGFR and HER2 kinases, impeding downstream signaling pathways involved in breast and other cancers.

Vemurafenib

918504-65-1sc-364643
sc-364643A
10 mg
50 mg
$117.00
$423.00
11
(1)

Specifically targets mutated BRAF, which is often overactive in melanomas, thereby reducing cancer cell proliferation.

Ibrutinib

936563-96-1sc-483194
10 mg
$156.00
5
(0)

Blocks BTK signaling in B-cell cancers, disrupting cell growth and survival pathways, especially in chronic lymphocytic leukemia.

Palbociclib

571190-30-2sc-507366
50 mg
$321.00
(0)

Inhibits CDK4/6, arresting the cell cycle progression in hormone receptor-positive breast cancers and other tumors.