Date published: 2026-5-4

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CROT Activators

CROT Activators are a diverse group of chemical compounds that play a significant role in enhancing the functional activity of Carnitine O-Palmitoyltransferase (CROT), mainly through their influence on lipid metabolism and mitochondrial function. Compounds like Carnitine and L-Carnitine are directly involved in the transport of fatty acids into mitochondria, a crucial step for β-oxidation where CROT is actively engaged. Acetyl-CoA is a key metabolic intermediate that indirectly influence CROT activity by regulating fatty acid metabolism. Additionally, Nicotinamide Adenine Dinucleotide (NAD+) plays a vital role in redox reactions within the mitochondria, impacting CROT's role in energy production. Bezafibrate, through activating PPARs, influences lipid metabolism pathways associated with CROT.

Alpha-Lipoic Acid, known for its effect on mitochondrial function, can impact CROT's role in energy production and fatty acid metabolism. Lastly, Coenzyme Q10, a key component in mitochondrial electron transport, indirectly influences CROT's function in energy metabolism. Collectively, these CROT Activators, through their targeted impact on various biochemical pathways, particularly those involving lipid metabolism and mitochondrial function, enhance the overall activity and efficiency of CROT, thereby facilitating its critical role in metabolic processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-Carnitine

541-15-1sc-205727
sc-205727A
sc-205727B
sc-205727C
1 g
5 g
100 g
250 g
$23.00
$34.00
$79.00
$179.00
3
(1)

Carnitine enhances CROT function by facilitating the transport of fatty acids into mitochondria, crucial for β-oxidation where CROT is actively involved.

Acetyl coenzyme A trisodium salt

102029-73-2sc-210745
sc-210745A
sc-210745B
1 mg
5 mg
1 g
$47.00
$92.00
$5826.00
3
(3)

Acetyl-CoA, as a substrate, is essential for fatty acid synthesis and oxidation processes, directly affecting CROT's function in lipid metabolism.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

NAD+ is vital in redox reactions within the mitochondria, impacting CROT's role in energy production and fatty acid oxidation.

Bezafibrate

41859-67-0sc-204650B
sc-204650
sc-204650A
sc-204650C
500 mg
1 g
5 g
10 g
$31.00
$46.00
$122.00
$204.00
5
(1)

Bezafibrate activates peroxisome proliferator-activated receptors (PPARs), influencing pathways where CROT is involved, particularly in lipid metabolism.

α-Lipoic Acid

1077-28-7sc-202032
sc-202032A
sc-202032B
sc-202032C
sc-202032D
5 g
10 g
250 g
500 g
1 kg
$69.00
$122.00
$212.00
$380.00
$716.00
3
(1)

Alpha-Lipoic Acid influences mitochondrial function, potentially affecting CROT's role in energy production and fatty acid metabolism.

Coenzyme Q10

303-98-0sc-205262
sc-205262A
1 g
5 g
$71.00
$184.00
1
(1)

Coenzyme Q10 is crucial for mitochondrial electron transport, indirectly influencing CROT's function in energy metabolism.