Coronin 7 (CORO7) activators are a class of chemicals that can modulate the functions of the CORO7 protein, which plays a pivotal role in various cellular processes. One group of CORO7 activators includes compounds like Latrunculin A and Cytochalasin D, which affect actin dynamics within the cell. Actin is a crucial component of the cytoskeleton, involved in processes such as cell motility, shape changes, and intracellular transport. CORO7 has been shown to interact with actin filaments, and by modulating actin dynamics, activators like Latrunculin A can potentially influence CORO7's functions. Additionally, compounds like Nocodazole, which disrupt microtubules, indirectly impact CORO7 as it interacts with actin. Microtubules and actin filaments are interconnected, and their regulation can have cascading effects on cellular processes, making these activators valuable tools for studying CORO7 biology.
Another set of CORO7 activators includes molecules like Brefeldin A, which disrupt the Golgi apparatus and vesicle trafficking. CORO7 is involved in vesicle trafficking, and alterations in this process can affect its functions. Thus, activators like Brefeldin A can indirectly impact CORO7-mediated vesicular transport. These activators provide researchers with the means to investigate the intricate roles of CORO7 in cellular processes, shedding light on the broader mechanisms governing cell biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Affects actin cytoskeleton, potentially influencing CORO7 through its role in actin-related processes. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Promotes actin polymerization, potentially enhancing CORO7's association with actin filaments. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics, indirectly affecting CORO7, which interacts with actin. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Disrupts actin cytoskeleton dynamics, indirectly impacting CORO7, which interacts with actin. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
Inhibits the ARP2/3 complex, which modulates actin filament branching and may indirectly affect CORO7. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Inhibitor of ROCK, affecting actin dynamics and potentially indirectly impacting CORO7. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits myosin II, a motor protein involved in actin-based processes, indirectly influencing CORO7. | ||||||
CK-869 | 388592-44-7 | sc-507274 | 5 mg | $163.00 | ||
ARP2/3 complex inhibitor, similar to CK-666, indirectly modulating actin branching and CORO7. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $151.00 $609.00 | 75 | |
Specific inhibitor of Rac1, a GTPase involved in actin dynamics, potentially impacting CORO7 indirectly. | ||||||